Christopher Wilhelm

Allen Institute for Artificial Intelligence
Publications13
h-index5
Citations833
Highly Influential Citations94
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CORD-19: The COVID-19 Open Research Dataset
TLDR
The mechanics of dataset construction are described, highlighting challenges and key design decisions, an overview of how CORD-19 has been used, and several shared tasks built around the dataset are described.
Construction of the Literature Graph in Semantic Scholar
TLDR
This paper reduces literature graph construction into familiar NLP tasks, point out research challenges due to differences from standard formulations of these tasks, and report empirical results for each task.
CD4 and CD8 T Cell Immune Activation during Chronic HIV Infection: Roles of Homeostasis, HIV, Type I IFN, and IL-7
TLDR
The molecular pathways that drive immune activation during chronic HIV infection are influenced by differences in the homeostatic regulation of the CD4 and CD8 T cell pools, which reflects the importance of maintaining a polyclonal CD4 T cell pool in host surveillance.
Ontology alignment in the biomedical domain using entity definitions and context
TLDR
This work proposes a method for enriching entities in an ontology with external definition and context information, and uses this additional information for ontology alignment, and develops a neural architecture capable of encoding the additional information when available.
Osmotic-stress-induced synthesis and degradation of inorganic polyphosphates in the alga Phaeodactylumtricornutum
TLDR
It is demonstrated that the alga Phaeodactylum tricornutum responds to hyperosmotic stress with a marked elongation of polyph phosphate molecules and a decrease in the total amount of extractable polyphosphate, while exposure to hypoosmotic Stress results in an increase in soluble shorter-chain polyphphosphates and a rise in total polyph phosphate content.
Targeting mitochondrial dysfunction can restore antiviral activity of NK cells in HIV/HCV coinfection
Cap-A-Growler
Increased IL-7 availability could overcome the anti-proliferative capacity of type-I IFN in Naïve CD8 T cells during HIV infection
332 HIV Infection leads to increased proliferation of T-cells by two distinct pathways that differentially affect CD4 and CD8 T-cells
Tetracycline Inhibits Pulmonary Inflammasome Activation via Caspase-1 in COVID-19 Patients with ARDS
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