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We address issues with the performance of IEEE 802.11, when used in the adhoc mode, in the presence of hidden terminals. We present results illustrating the strong dependence of channel capture behavior on the SNR observed on contending hidden connections. Experimental work has illustrated that in a hidden terminal scenario, the connection having the(More)
In this paper we investigate the performance of common capture models in terms of the fairness properties they reflect across contenting hidden connections. We propose a new capture model, Message Retraining,as a means of providing an accurate description of experimental data. Using two fairness indices we undertake a quantitative study of the accuracy with(More)
— This paper addresses recent experimental measurements from an IEEE 802.11 ad hoc network testbed, which indicate a strong signal strength dependence in the ability of a hidden terminal to gain access to the radio channel. We present analytical results investigating the 'hidden terminal jamming' ability of the IEEE 802.11 DSSS physical layer. Results(More)
This paper addresses experimental measurements from an IEEE 802.11 ad hoc network testbed, which indicate a strong signal strength dependence in the ability of a hidden terminal to gain access to the radio channel. We present analytical results investigating thèhidden terminal jamming' ability of the IEEE 802.11 DSSS physical layer. Results indicate that in(More)
Pathways regulating neuronal vulnerability are poorly understood, yet are central to identifying therapeutic targets for degenerative neurological diseases. Here, we characterize mechanisms underlying neurodegeneration in Niemann-Pick type C (NPC) disease, a lysosomal storage disorder characterized by impaired cholesterol trafficking. To date, the relative(More)
Vorinostat is a histone deacetylase inhibitor that induces differentiation, growth arrest, and/or apoptosis of malignant cells both in vitro and in vivo and has shown clinical responses in f30% of patients with advanced mycosis fungoides and Sézary syndrome cutaneous T-cell lymphoma (CTCL). The purpose of this study was to identify biomarkers predictive of(More)
Aberrant kinase activation resulting from mutation, amplification, or translocation can drive growth and survival in a subset of human cancer. FGFR2 is amplified in breast and gastric cancer, and we report here the first characterization of FGFR2 gene amplification in colorectal cancer in the NCI-H716 colorectal cancer cell line. FGFR2 is highly expressed(More)
For the last 100 years secretin has been extensively studied for its hormonal effects on digestion. Recent observations that the deficits in social reciprocity skills seen in young (3-4-year-old) autistic children are improved after secretin infusions suggest an additional influence on neuronal activity. We show here that i.v. administration of secretin in(More)
— Simulation plays an important role in the performance evaluation of MAC protocols. Building simulation models which are able to accurately model physical behaviour is fundamental to the outcome of such techniques. Through both qualitative and quantitative comparison of experimental trace data against simulation results obtained using delay, power, and(More)
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