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Many value-added and content delivery services are being offered via service level agreements (SLAs). These services can be interconnected to form a service overlay network (SON) over the Internet. Service composition in SON has emerged as a cost-effective approach to quickly creating new services. Previous research has addressed the reliability,(More)
Regulation of transcription initiation is generally attributable to activator/repressor proteins that bind to specific DNA sequences. However, regulators can also achieve specificity by binding directly to RNA polymerase (RNAP) and exploiting the kinetic variation intrinsic to different RNAP-promoter complexes. We report here a previously unknown(More)
It has become increasingly desirable for companies worldwide to outsource their complex e-business infrastructure under the utility computing paradigm by means of service level agreements (SLAs). A successful utility computing provider must be able not only to satisfy its customers' demand for high service-quality standards, but also to fulfill its(More)
We study dependable group communication for large-scale and delay-sensitive mission critical applications. The goal is to design a protocol that imposes low loads on bottleneck network links and provides both stable throughput and fast delivery of multicast messages even in the presence of frequent node and link failures. To this end, we propose our GoCast(More)
The routing tables of Distributed Hash Tables (DHTs) can vary from size <i>O</i>(1) to <i>O</i>(<i>n</i>). Currently, what is lacking is an analytic framework to suggest the optimal routing table size for a given workload. This paper (1) compares DHTs with <i>O</i>(1) to <i>O</i>(<i>n</i>) routing tables and identifies some good design points; and (2)(More)
It is imperative for a competitive e-business service provider to be positioned to manage the execution of its service level agreement (SLA) contracts in business terms (e.g., minimizing financial penalties for service-level violations, maximizing service-level measurement based customer satisfaction metrics). This paper briefly describes the design(More)
It is imperative for a competitive e-business outsourcing service provider to manage the execution of its service level agreement (SLA) contracts in business terms (e.g., minimizing financial penalties for service-level violations, maximizing service-level measurement based customer satisfaction metrics, etc.). In order to do that, the provider must possess(More)
INTRODUCTION There has been a significant rise in the number of HIV positive men who have sex with men (MSM) co-infected with hepatitis C (HCV). Most infections are thought to occur through high risk sexual practices, exacerbated by drug use. Previous data has suggested no need for routine screening in HIV negative MSM. We looked at HCV antibody testing and(More)
Despite several trials showing reductions in tone and improvements in gait, the relation between botulinum toxin A (BTX-A) dose and response has rarely been investigated. A double-blind randomized comparison of two doses of BTX-A in children with spastic hemiplegic cerebral palsy (n=48, mean age 7 years 6 months, range 3 to 15 years) was undertaken. The two(More)