Christopher W. B. Jensen

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This study aimed to evaluate genetic variability in the FUS and TDP-43 genes, known to be mainly associated with amyotrophic lateral sclerosis (ALS), in patients with the diagnoses of frontotemporal lobar degeneration (FTLD) and corticobasal syndrome (CBS). We screened the DNA of 228 patients for all the exons and flanking introns of FUS and TDP-43 genes.(More)
Cyclosporine (CsA), an immunosuppressive drug widely used in clinical organ transplantation, causes a variety of side effects, including parenchymal complications of nephrotoxicity and hepatotoxicity. Erythromycin ethinylsuccinate (EES), a macrolide antibiotic frequently administered to transplant patients afflicted with pneumonias caused by Mycoplasma(More)
FK 506 was used as a primary immunosuppressive agent in 125 cases of renal transplantation in a randomized trial comparing FK 506/prednisone with FK 506/azathioprine/prednisone. With a mean follow-up of 5.5 +/- 2.5 months, there has been a 6-month actuarial patient survival of 99% and graft survival of 88%. There is no difference thus far between the(More)
N EPHROTIC syndrome developing after renal transplantation has many etiologies. Recurrent focal sclerosing glomerulonephritis is' ane of the leading causes.! Other etiologies include: (1) transplant glomerulopathy; (2) chronic rejection; (3) de novo membranous glomerulonephritis (ON); and (4) other recurrent glomerulonephropathies (membranoproliferative(More)
N EPHROTIC syndrome is a broad group of disorders with diverse etiologies. In common. all have proteinuria. edema. hypercholesterolemia. and hypoalbuminemia. Steroids have proven effective in some histologic groups. but many are resistant to steroids and progress to end-stage renal disease. Transplant glomerulopathy and chronic rejection also contribute(More)