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  • Christopher D. Shaffer, Consuelo Alvarez, Cheryl Bailey, Daron Barnard, Satish Bhalla, Chitra Chandrasekaran +47 others
  • 2010
Genomics is not only essential for students to understand biology but also provides unprecedented opportunities for undergraduate research. The goal of the Genomics Education Partnership (GEP), a collaboration between a growing number of colleges and universities around the country and the Department of Biology and Genome Center of Washington University in(More)
Epidermal growth factor receptor (EGFR) signalling is a potent driver of glioblastoma, a malignant and lethal form of brain cancer. Disappointingly, inhibitors targeting receptor tyrosine kinase activity are not clinically effective and EGFR persists on the plasma membrane to maintain tumour growth and invasiveness. Here we show that endolysosomal pH is(More)
Many network visualizations make the assumption that an administrator has previously determined the subset of data that should be visualized. Yet the problem remains that if the visualization provides no insight into the network events that warrant further consideration , then the administrator must go back to the data to determine what should be visualized(More)
Glioblastoma (GB) is a highly invasive and lethal brain tumor due to its universal recurrence. Although it has been suggested that the electroneutral Na(+)-K(+)-Cl(-) cotransporter 1 (NKCC1) can play a role in glioma cell migration, the precise mechanism by which this ion transporter contributes to GB aggressiveness remains poorly understood. Here, we(More)
Residual clinical samples represent a very appealing source of biomaterial for translational and clinical research. We describe the implementation of an opt-in biobank, with consent being obtained at the time of registration and the decision stored in our electronic health record, Epic. Information on that decision, along with laboratory data, is(More)
– An approach for evaluating the performance of decentralized estimation systems under non-ideal communications is presented. Recent studies have shown that transmission disruptions occur frequently in tactical wireless networks due to a variety of unpredictable factors, such as unintentional interference or jamming. Yet the impact of non-ideal(More)
While existing resource management software systems each have distinct and advanced capabilities, the way in which a user submits a basic job is generally similar across resource mangement systems. Recognizing this, the HPC Profile Working Group in the Open Grid Forum (OGF) has recently created a set of standards to define a common Web-services-based(More)
Prostatitis is an inflammation of the prostate gland which affects approximately 10% of men. Despite its frequency, diagnosing prostatitis and monitoring patient response to treatment remains frustrating. As the prostate contributes a substantial percentage of proteins to seminal plasma, we hypothesized that a protein biomarker of prostatitis might be found(More)