Christopher S. Thompson

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Some people have much better memory than others, and there is compelling evidence that a considerable proportion of this variation in memory ability is genetically inherited. A form of synaptic plasticity known as long-term potentiation (LTP) is the principal candidate mechanism underlying memory formation in neural circuits, and it might be expected,(More)
The Community Earth System Model (CESM) is a widely used community model for studying the climate system on the Earth. The CESM model is both data and computationally intensive, making it difficult for users to set up and run CESM simulations using local resources. In this paper, we describe an integrated climate modeling environment that supports CESM(More)
A growing body of literature has explored the influence of physical activity on brain structure and function. While the mechanisms of this relationship remain largely speculative, recent research suggests that one of the effects of physical exercise is an increase in synaptic long-term potentiation (LTP). This has not yet been explored directly in humans(More)
OBJECTIVE To evaluate the New York State Expanded Food and Nutrition Education Program using economic methodology. DESIGN Data were collected by nutrition educators in a pretest, posttest design with an epidemiological modeling approach to assess costs and estimate potential health benefits of the state program. SETTING Cooperative Extension, 35(More)
Single nucleotide polymorphisms in the brain-derived neurotrophic factor (BDNF) gene and the catechol-O-methyltransferase (COMT) gene influence brain structure and function, as well as cognitive abilities. They are most influential in the hippocampus and prefrontal cortex (PFC), respectively. Recall and recognition are forms of memory proposed to have(More)
This paper describes an XSEDE Extended Collaboration Support Service (ECSS) effort on scaling a campus-developed online BLAST service (BLASTer) into an XSEDE gateway to help bridge the gap between genomic researchers and advanced computing and data environments like those found in the Extreme Science and Engineering Discovery Environment (XSEDE) network.(More)
In this paper, we describe a "gateway as a service" approach to help researchers bring their applications online quickly and make them available for the broad user community. This approach builds on the HUBzero technology and leverages the XSEDE HPC resources. It enables individual scientists and small research groups to quickly develop, deploy, and share(More)
“What we would like,” said Obuchi Yasuo, the former mayor of a farm town in northeastern Japan, “is for young people and their employers in Tokyo to consider lifestyle alternatives never possible before. Male and female employees could maintain a spacious residence here in the countryside while commuting to work in the city.” Gazing out across the terraced(More)
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