PURPOSE To investigate symptom profiles and clinical signs in subjects with dry eye and normal subjects in a cross-sectional multicenter study. METHODS Subjects aged 35 to 65 were recruited according to dry eye diagnostic codes and telephone interview and completed the Dry Eye Questionnaire 2001, among others, and underwent dry eye clinical tests. … (More)
Atraumatically collected nonstimulated (less than 1 microliter/min) and stimulated (greater than 50 microliters/min) tears from 30 clinically normal subjects were fractionated by size exclusion high-performance liquid chromatography (SE-HPLC). Enzyme-linked immunosorbent assay (ELISA) and kinetic assays were applied to relevant HPLC fractions to… (More)
PURPOSE To assess the relative burden of dry eye in daily life by comparing Short Form-36 (SF-36) responses from individuals with and without dry eye against U.S. norms. METHODS Assessment of 210 people, 130 with non-Sjogren's keratoconjunctivitis sicca (non-SS KCS), 32 with Sjogren's Syndrome (SS), and 48 control subjects. The study population data and… (More)
OBJECTIVES Risperidone is approved for the treatment of serious behavioral problems in children with autism spectrum disorder (ASD). This study examined the effects of risperidone on cardiac conduction in children with ASD. METHODS Data were collected from an 8-week, five-site trial conducted by the Research Units on Pediatric Psychopharmacology Autism… (More)
Late occurrence of atrioventricular nodal block is an extremely rare occurrence after radiofrequency catheter modification of the slow pathway and has yet to be reported after cryoablation. We report a case of late transient advanced second degree atrioventriuclar block after cryomodification of the slow pathway.