Christopher S. Cooper

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A ‘second generation’ approach to the provision of Grid middleware is now emerging which is built on service-oriented architecture and web services standards and technologies. However, advanced Grid applications have significant demands that are not addressed by present-day web services platforms. As one prime example, current platforms do not support the(More)
The evaluation and management of fetuses/children with antenatal hydronephrosis (ANH) poses a significant dilemma for the practitioner. Which patients require evaluation, intervention or observation? Though the literature is quite extensive, it is plagued with bias and conflicting data, creating much confusion as to the optimal care of patients with ANH. In(More)
Significant progress has been made in the design and development of Grid middleware which, in its present form, is founded on service-oriented architecture and web services technologies. Nevertheless, Grid middleware is still severely limited in key areas. In this paper we discuss work that aims to address some of these limitations. First, we consider how(More)
OBJECTIVE Urinary tract (UT) dilation is sonographically identified in 1-2% of fetuses and reflects a spectrum of possible uropathies. There is significant variability in the clinical management of individuals with prenatal UT dilation that stems from a paucity of evidence-based information correlating the severity of prenatal UT dilation to postnatal(More)
PURPOSE We present a consensus view of members of the International Children's Continence Society (ICCS) together with pediatric gastroenterologists, experts in the field of functional gastrointestinal disorders, on the management of functional constipation in children with lower urinary tract symptoms. MATERIALS AND METHODS Discussions were held by the(More)
IMPORTANCE Approximately 1.4 million male circumcisions (MCs) are performed annually in US medical settings. However, population-based estimates of MC-associated adverse events (AEs) are lacking. OBJECTIVES To estimate the incidence rate of MC-associated AEs and to assess whether AE rates differed by age at circumcision. DESIGN We selected 41 possible(More)
OBJECTIVES Pelvic immobilization constitutes a necessary component of successful bladder exstrophy closure. The efficacy of spica cast immobilization has been reported as markedly inferior to external fixation, with success rates below 25%. We reviewed our experience with spica cast immobilization following bladder closure. PATIENTS AND METHODS We(More)
The rise of mobile computing and wireless network technology means that, increasingly, applications must adapt to their environment, in particular network connectivity and resource availability. This paper outlines the TOAST middleware platform which provides component-oriented CORBA support for adaptive distributed multimedia applications. In particular,(More)
Significant progress has been made in the design and development of Grid middleware which, in its present form, is founded on web services technologies. However, we argue that present-day Grid middleware is severely limited in supporting projected nextgeneration applications which will involve pervasive and heterogeneous networked infrastructures, and(More)
PURPOSE Accepted management of vesicoureteral reflux includes surgical correction or prophylactic antibiotics with the hope for resolution as the child grows. The physician must consider surgery when reflux does not resolve despite uneventful years on prophylactic antibiotics. An alternative is cessation of the antibiotics. We report on the outcome of(More)