Christopher S Combs

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BACKGROUND/AIMS 18F-fluorodeoxyglucose uptake allows estimation of glucose metabolism by tumor cells using positron emission tomography (PET). We evaluated the role of PET imaging in the diagnosis of hepatocellular carcinoma. METHODS PET images were collected after intravenous injection of 8-12 mCi of 18F-FDG in 20 patients with hepatocellular carcinoma(More)
Free radical mediated lipid peroxidation (LPO) has been implicated in the pathogenesis of ischemic-reperfusion injury (IRI). To address the renoprotective effect(s) of LPO inhibition, the efficacy of the 21 aminosteroid U74389G was evaluated in three IRI models. In Model 1 51 unilateral nephrectomized rats that underwent 60 min of warm ischemia followed by(More)
A 37-year-old man undergoing liver transplantation for cirrhosis caused by chronic hepatitis C and alcoholism developed large numbers of alpha1-antitrypsin (AAT) globules within hepatocytes of the transplanted liver during a 5-month period. This finding occurred simultaneously with severe recurrent hepatitis C. The AAT phenotype of this patient changed from(More)
Project TRANSITION studied, as part of a three year field initiated research project, the effect of training selected personal health skills and their relationship to adaptive behavior. The subjects were moderately, severely, and profoundly retarded individuals residing in a state-operated developmental center. Eighty-eight subjects were selected and then(More)
Few studies on naphthalene vapor fluorescence have been conducted at low temperature and pressure conditions. The current study focuses on conducting measurements of naphthalene quenching and absorption cross section in a temperature- and pressure-regulated test cell with 266 nm laser excitation. The test-cell measurements were of the(More)
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