Learn More
We examine the distribution and structure of human genetic diversity for 710 individuals representing 31 populations from Africa, East Asia, Europe, and India using 100 Alu insertion polymorphisms from all 22 autosomes. Alu diversity is highest in Africans (0.349) and lowest in Europeans (0.297). Alu insertion frequency is lowest in Africans (0.463) and(More)
We describe aspects of genetic diversity in several ethnic populations of the Caucasus Mountains of Daghestan using mitochondrial DNA sequences and a sample of 100 polymorphic Alu insertion loci. The mitochondrial DNA (mtDNA) sequences are like those of Europe. Principal coordinates and nearest neighbor statistics show that there is little detectable(More)
BACKGROUND/AIMS The L1 retrotransposable element family is the most successful self-replicating genomic parasite of the human genome. L1 elements drive replication of Alu elements, and both have had far-reaching impacts on the human genome. We use L1 and Alu insertion polymorphisms to analyze human population structure. METHODS We genotyped 75 recent,(More)
Current day network processors incorporate several architectural features including symmetric multi-processing (SMP), block multi-threading, and multiple memory elements to support the high performance requirements of networking applications. We present an automated system-level design technique for application development on such architectures. The(More)
A major goal of biomedical research is to develop the capability to provide highly personalized health care. To do so, it is necessary to understand the distribution of interindividual genetic variation at loci underlying physical characteristics, disease susceptibility, and response to treatment. Variation at these loci commonly exhibits geographic(More)
Genetic, ethnographic, and historical evidence suggests that the Hindu castes have been highly endogamous for several thousand years and that, when movement between castes does occur, it typically consists of females joining castes of higher social status. However, little is known about migration rates in these populations or the extent to which migration(More)
The increasing demand for programmable platforms that enable high bandwidth communication traffic processing has led to the advent of chip multi-processor (CMP) based multi-threaded network processor (NP) architectures. The CMP based architectures include a multitude of heterogeneous memory units ranging from on-chip register banks, local data memories, and(More)
Network processors incorporate several architectural features, including symmetric multiprocessing (SMP), block multithreading, and multiple memory elements, to support the high-performance requirements of current day applications. This article presents automated system-level design techniques for application development on such architectures. We propose(More)
The high performance requirements of networking applications has led to the advent of programmable network processor (NP) architectures that incorporate symmetric multiprocessing, and block multi-threading. The paper presents an automated system-level design technique for process mapping on such architectures with an objective of maximizing the worst case(More)
Network processor architectures incorporate block multi-threading to alleviate the performance degradation due to memory access latencies. Application design on such architectures requires the determination of the number of threads, and mapping of data items to the various memory elements such that the overall throughput is maximized. The paper presents a(More)
  • 1