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Vascular endothelial growth factor (VEGF-A) is a major regulator of blood vessel formation and function. It controls several processes in endothelial cells, such as proliferation, survival, and migration, but it is not known how these are coordinately regulated to result in more complex morphogenetic events, such as tubular sprouting, fusion, and network(More)
Recent technological trends indicate that future datacen-ter networks will incorporate High Performance Computing network features, such as ultra-low latency and CPU bypassing. How can these features be exploited in datacenter-scale systems infrastructure? In this paper , we explore the design of a distributed in-memory key-value store called Pilaf that(More)
—A significant challenge in the development of robust wireless networking protocols is often the need to prototype and test these protocols in a small-scale setting before they can be widely deployed. Two contrasting prototyping and testing methods are currently used, requiring a choice between convenience and accuracy. The first involves simulating a(More)
—The extensive recent research in protocols development for wireless networks must be complemented with simple yet efficient prototyping and evaluation mechanism. MiNT-2 is a miniaturized multi-hop wireless network testbed that addresses this challenge by combining the benefits of existing protocol evaluations strategies: simulations and custom built large(More)
Cuticular hydrocarbons (CHCs) play an essential role in mate recognition in insects but the form and intensity of sexual selection on CHCs has only been evaluated in a handful of studies, and never in a natural population. We quantified sexual selection operating on CHCs in a wild population of sagebrush crickets, a species in which nuptial feeding by(More)
Female mate choice is one mechanism of sexual selection and, provided there is adequate genetic variation in the male traits that are the target of this selection, they will evolve via female choice. Cuticular hydrocarbons (CHCs) are important in Drosophila mate choice, but relatively little is known about the underlying genetic architecture of CHC profiles(More)
permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. Males can gather information on the risk and intensity of sperm competition from their social environment. Recent studies have implicated chemosensory cues, for instance cuticular hydrocarbons (CHCs) in insects, as a key source of this(More)
Females of many species obtain benefits by mating polyandrously, and often prefer novel males over previous mates. However, how do females recognise previous mates, particularly in the face of cognitive constraints? Female crickets appear to have evolved a simple but effective solution: females imbue males with their own cuticular hydrocarbons (CHCs) at(More)
Our expectations for the evolution of chemical signals in response to sexual selection are uncertain. How are chemical signals elaborated? Does sexual selection result in complexity of the composition or in altered quantities of expression? We addressed this in Drosophila pseudoobscura by examining male and female cuticular hydrocarbons (CHs) after 82(More)