Christopher Michael James

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We present the case of a patient diagnosed as having presumed idiopathic thrombocytopenic purpura (ITP) who subsequently developed chronic myelomonocytic leukaemia (CMML) after an interval of 16 months. A variety of peripheral cytopenias are commonly seen in myelodysplastic disorders (MDS), and autoimmune phenomena, including secondary ITP, are well(More)
The case is reported of a physically fit man, who, while training for a triathlon, developed pulmonary oedema secondary to swimming in cold water. Pulmonary oedema is usually caused by a combination of exercise and cold water, resulting in an increase in cardiac preload and after load, which causes an increase in pulmonary capillary pressure. Most cases(More)
Standard treatment for patients with metastatic colorectal carcinoma (MCC) involves treatment with weekly 5-flurouracil (5-FU) chemotherapy by continuous infusion, requiring the insertion of a central venous catheter (CVC). One of the main complications of CVCs is venous thromboembolic disease (VTE), with an incidence varying between 3 and 54% in different(More)
We report the case of a 72-year-old lady who presented with fatigue and bruising. Initial investigations were compatible with iron deficiency anaemia and idiopathic thrombocytopenic purpura (ITP). The anaemia and recent heartburn symptoms led to endoscopy, which revealed an extensive oesophageal squamous cell carcinoma. The tumour was inoperable due to(More)
A case report is presented of a 33-year-old woman who awoke with distal paresthesias, mild incoordination, and progressive weakness. Examination 3 days later demonstrated weakness of the extremities, which was greater in distal muscles than in proximal ones! mild facial weakness, distal vibratory loss, and areflexia. Electrodiagnostic studies provided(More)
OBJECTIVES To determine the effect of access design on intracoronal bleaching with 35% carbamide peroxide on discolored teeth. MATERIALS AND METHODS Forty-two intact maxillary central incisors were selected, sectioned and artificially stained using whole blood. Color measurements were performed with a spectrophotometer: before staining (T1), after(More)
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