Christopher Marshall

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A microbial community originating from brewery waste produced methane, acetate, and hydrogen when selected on a granular graphite cathode poised at -590 mV versus the standard hydrogen electrode (SHE) with CO(2) as the only carbon source. This is the first report on the simultaneous electrosynthesis of these commodity chemicals and the first description of(More)
The search for microorganisms that are capable of catalyzing the reduction of an electrode within a fuel cell has primarily been focused on bacteria that operate mesobiotically. Bacteria that function optimally under extreme conditions are beginning to be examined because they may serve as more effective catalysts (higher activity, greater stability, longer(More)
Microbial electrosynthesis is the biocathode-driven production of chemicals from CO2 and has the promise to be a sustainable, carbon-consuming technology. To date, microbial electrosynthesis of acetate, the first step in order to generate liquid fuels from CO2, has been characterized by low rates and yields. To improve performance, a previously established(More)
Antiviral immunity requires recognition of viral pathogens and activation of cytotoxic and Th cells by innate immune cells. In this study, we demonstrate that hepatitis C virus (HCV) core and nonstructural protein 3 (NS3), but not envelope 2 proteins (E2), activate monocytes and myeloid dendritic cells (DCs) and partially reproduce abnormalities found in(More)
BACKGROUND & AIMS Persistent inflammation contributes to progression of liver damage in chronic HCV (cHCV) infection. Repeated exposure to toll-like receptor (TLR) ligands results in tolerance, a protective mechanism aimed at limiting inflammation. METHODS Monocytes/macrophages were repeatedly stimulated via proinflammatory cytokine-inducing TLRs and(More)
UNLABELLED The "Candidatus Synechococcus spongiarum" group includes different clades of cyanobacteria with high 16S rRNA sequence identity (~99%) and is the most abundant and widespread cyanobacterial symbiont of marine sponges. The first draft genome of a "Ca. Synechococcus spongiarum" group member was recently published, providing evidence of genome(More)
<b>Background</b> The labour intensive and error prone nature of the systematic review process has led to the development and use of a range of tools to provide automated support. <b>Aim</b> The aim of this research is to evaluate a set of candidate tools that provide support for the overall systematic review process. <b>Method</b> A feature analysis is(More)
The demand for chemicals and fuels will continue to grow simultaneously with the costly requirement to treat solid waste, wastewater, and regarding climate change, carbon dioxide. A dual benefit is at hand if waste could be converted to valuable chemicals. The application of stable chemical producing microbiomes adapted to these waste streams may turn this(More)
Background: Systematic literature reviews (SLRs) have become an established methodology in software engineering (SE) research however they can be very time consuming and error prone. Aim: The aims of this study are to identify and classify tools that can help to automate part or all of the SLR process within the SE domain. Method: A mapping study was(More)