Christopher M Jermak

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PURPOSE To measure the buffering capacity of bovine vitreous to HCl, NaOH, and triamcinolone acetonide. METHODS Vitreous was dissected from 10 bovine globes, homogenized, and divided into 5.0-mL aliquots. The carbonate/bicarbonate buffer of the vitreous was maintained by performing all subsequent titrations under an atmosphere of 5% CO2/95% air. The pH(More)
Triamcinolone acetonide has been effectively used in ocular therapeutics for over 50 years. Its use has increased dramatically in recent years for periocular and intraocular treatment of retinal vasculature disease and uveitis. This comprehensive review discusses the pharmacokinetics of triamcinolone acetonide and summarizes its uses in a number of(More)
BACKGROUND AND OBJECTIVE To assess the retinal toxicity of varying concentrations of intravitreally injected gatifloxacin and levofloxacin. MATERIALS AND METHODS In this experimental, controlled study, levofloxacin (initial concentration = 25 mg/mL) and gatifloxacin (initial concentration = 2 mg/mL) were titrated using 5% dextrose solution to(More)
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