• Publications
  • Influence
Interleukin‐17A‐Induced Human Mesenchymal Stem Cells Are Superior Modulators of Immunological Function
Interferon‐γ (IFN‐γ)‐preactivated mesenchymal stem cells (MSC‐γ) are highly immunosuppressive but immunogenic in vivo due to their inherent expression of major histocompatibility (MHC) molecules.Expand
  • 57
  • 4
C4d‐negative antibody‐mediated rejection with high anti‐angiotensin II type I receptor antibodies in absence of donor‐specific antibodies
Acute antibody‐mediated rejection can occur in absence of circulating donor‐specific antibodies. Agonistic antibodies targeting the anti‐angiotensin II type 1 receptor (anti‐AT1R) are emerging asExpand
  • 36
  • 3
The immune phenotype may relate to cancer development in kidney transplant recipients.
High regulatory T-cell (Treg) numbers predict recurrent cutaneous squamous cell carcinoma in kidney transplant recipients, and the Treg immune phenotype may identify kidney transplant recipients atExpand
  • 34
  • 2
Angiotensin II type-1 receptor antibody (AT1Rab) associated humoral rejection and the effect of peri operative plasma exchange and candesartan.
Angiotensin II type 1 antibodies (AT1Rab) can mediate antibody mediated rejection (AMR). Pre transplant AT1Rab levels, and risk of rejection were assessed in Kidney Transplant Recipients (KTR)Expand
  • 16
Peripheral natural killer cell and allo-stimulated T-cell function in kidney transplant recipients associate with cancer risk and immunosuppression-related complications.
Reducing immunosuppression has been proposed as a means of preventing cancer in kidney transplant recipients but this can precipitate graft rejection. Here we tested whether anti-tumor natural killerExpand
  • 17
Single Cell Level Quantification of Nanoparticle-Cell Interactions Using Mass Cytometry.
Quantification of cell-associated nanoparticles (NPs) is a paramount question in both nanomedicine and nanotoxicology. Inductively coupled plasma mass spectrometry is a well-established method toExpand
  • 13
Reductions in immunosuppression after haematological or solid organ cancer diagnosis in kidney transplant recipients
Few data exist on how immunosuppression is altered in kidney transplant recipients (KTR) following a diagnosis of cancer. This study investigated how immunosuppression was altered in KTR after cancerExpand
  • 9
FOXP3 and miR-155 cooperate to control the invasive potential of human breast cancer cells by down regulating ZEB2 independently of ZEB1
Control of oncogenes, including ZEB1 and ZEB2, is a major checkpoint for preventing cancer, and loss of this control contributes to many cancers, including breast cancer. Thus tumour suppressors,Expand
  • 8
  • PDF
Immune profiling and cancer post transplantation.
Half of all long-term (> 10 year) australian kidney transplant recipients (KTR) will develop squamous cell carcinoma (SCC) or solid organ cancer (SOC), making cancer the leading cause of death with aExpand
  • 7
Thymus-Derived Regulatory T Cells Exhibit Foxp3 Epigenetic Modification and Phenotype Attenuation after Mating in Mice
Key Points Seminal fluid primes Treg cells to elicit tolerance of male alloantigens. Neuropilin-1+ Tregs of likely thymic origin are prevalent amongst responding T cells. Neuropilin-1+ Tregs exhibitExpand
  • 6