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Journals and Conferences
H2S is a gas easily identified by its distinctive odor. Although environmental exposure to H2S has been viewed alternately as therapeutic or toxic through the centuries, H2S has recently regained… (More)
Dietary restriction (DR) as a means to increase longevity is well-established in a number of model organisms from yeast to primates. DR also improves metabolic fitness and increases resistance to… (More)
Aging and chemotherapeutics damage hematopoietic stem cells (HSCs), leading to dysregulation of asymmetric division and subsequent immunosuppression and blood-related diseases. In this issue, Cheng… (More)
Angiogenesis, the formation of new blood vessels by endothelial cells (ECs), is an adaptive response to oxygen/nutrient deprivation orchestrated by vascular endothelial growth factor (VEGF) upon… (More)
Aged mice preconditioned with a running routine were resistant to acute systemic sepsis compared with non-runner.
Two weeks of rapamycin administration in young and old female mice leads to long-term improvements in ovarian function and reproductive longevity.
Chronic 1% metformin treatment is nephrotoxic in mice, but this dose may nonetheless confer health benefits if given intermittently rather than continuously. Here, we examined the effects of 1%… (More)
Vaccination with potato virus X nanoparticles enhances the efficacy of traditional doxorubicin anticancer therapy against a mouse melanoma tumor model.
Repeated activation of target of rapamycin (TOR) signaling during tissue regeneration results in impaired stem cell maintenance and promotes aging.
Obesity increases risk for liver toxicity by the anti-leukemic agent asparaginase, but the mechanism is unknown. Asparaginase activates the integrated stress response (ISR) via sensing amino acid… (More)