Christopher M. Callahan

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CONTEXT Few depressed older adults receive effective treatment in primary care settings. OBJECTIVE To determine the effectiveness of the Improving Mood-Promoting Access to Collaborative Treatment (IMPACT) collaborative care management program for late-life depression. DESIGN Randomized controlled trial with recruitment from July 1999 to August 2001. (More)
CONTEXT Most older adults with dementia will be cared for by primary care physicians, but the primary care practice environment presents important challenges to providing quality care. OBJECTIVE To test the effectiveness of a collaborative care model to improve the quality of care for patients with Alzheimer disease. DESIGN, SETTING, AND PATIENTS(More)
OBJECTIVE To design a brief cognitive screener with acceptable sensitivity and specificity for identifying subjects with cognitive impairment. DESIGN Cohort one is assembled from a community-based survey coupled with a second-stage diagnostic evaluation using formal diagnostic criteria for dementia. Cohort two is assembled from referrals to a specialty(More)
BACKGROUND: Primary care physicians are positioned to provide early recognition and treatment of dementia. We evaluated the feasibility and utility of a comprehensive screening and diagnosis program for dementia in primary care. METHODS: We screened individuals aged 65 and older attending 7 urban and racially diverse primary care practices in Indianapolis.(More)
CONTEXT Low-income seniors frequently have multiple chronic medical conditions for which they often fail to receive the recommended standard of care. OBJECTIVES To test the effectiveness of a geriatric care management model on improving the quality of care for low-income seniors in primary care. DESIGN, SETTING, AND PATIENTS Controlled clinical trial of(More)
BACKGROUND Although effective treatment of depressed patients requires regular follow-up contacts and symptom monitoring, an efficient method for assessing treatment outcome is lacking. We investigated responsiveness to treatment, reproducibility, and minimal clinically important difference of the Patient Health Questionnaire-9 (PHQ-9), a standard(More)
OBJECTIVES To compare the medical comorbidity of older patients with and without dementia in primary care. DESIGN Cross-sectional study. SETTING Wishard Health Services, which includes a university-affiliated, urban public hospital and seven community-based primary care practice centers in Indianapolis. PARTICIPANTS Three thousand thirteen patients(More)
OBJECTIVE Facilitate primary care physicians' compliance with recommended standards of care for late life depression by reducing barriers to recognition and treatment. DESIGN Randomized controlled clinical trial of physician-targeted interventions. SETTING Academic primary care group practice caring for an urban, medically indigent patient population.(More)
OBJECTIVE To compare the ability of commonly used measures of medical comorbidity (ambulatory care groups [ACGs], Charlson comorbidity index, chronic disease score, number of prescribed medications, and number of chronic diseases) to predict mortality and health care costs over 1 year. STUDY DESIGN AND SETTING A prospective cohort study of(More)
Oxidative stress has been implicated both in the aging process and in the pathological changes associated with Alzheimer's disease. Antioxidants, which have been shown to reduce oxidative stress in vitro, may represent a set of potentially modifiable protective factors for poor memory, which is a major component of the dementing disorders. The authors(More)