Christopher Laing

Learn More
BACKGROUND Whether remote ischemic preconditioning (transient ischemia and reperfusion of the arm) can improve clinical outcomes in patients undergoing coronary-artery bypass graft (CABG) surgery is not known. We investigated this question in a randomized trial. METHODS We conducted a multicenter, sham-controlled trial involving adults at increased(More)
Renal tubular acidosis is a metabolic acidosis due to impaired acid excretion by the kidney. Hyperchloraemic acidosis with a normal anion gap and normal (or near normal) glomerular filtration rate, and in the absence of diarrhoea, defines this disorder. However, systemic acidosis is not always evident and renal tubular acidosis can present with(More)
The role of triage in digital forensics is disputed, with some practitioners questioning its reliability for identifying evidential data. Although successfully implemented in the field of medicine, triage has not established itself to the same degree in digital forensics. This article presents a novel approach to triage for digital forensics. Case-Based(More)
Communication networks involve the transmission and reception of large volumes of data. Research indicates that network traffic volumes will continue to increase. These traffic volumes will be unprecedented and the behaviour of global information infrastructures when dealing with these data volumes is unknown. It has been tshown that complex systems(More)
BACKGROUND Primary Sjögren syndrome (pSS) is a common autoimmune condition which primarily affects epithelial tissue, often including the kidney causing either tubulointerstitial nephritis (TIN) or more rarely, an immune complex related glomerulonephritis. METHODS We describe the clinical, biochemical and histological characteristics of 12 patients with(More)
BACKGROUND/AIMS Calcium homeostasis requires regulated cellular and interstitial systems interacting to modulate the activity and movement of this ion. Disruption of these systems in the kidney results in nephrocalcinosis and nephrolithiasis, important medical problems whose pathogenesis is incompletely understood. METHODS We investigated 25 patients from(More)
Centre for Nephrology and Department of Physiology, Royal Free and University College Medical School, University College London, Rowland Hill Street, London NW3 2PF and Department of Biochemistry, School of Medical Sciences, University Walk, University of Bristol, Bristol BS8 1TD, UK, Institute of Physiology and Center for Integrative Human Physiology,(More)
Diagnosing exceptions in multi-agent systems ( M S ) is a complex task due to the distributed nature af the data and control in such systems. This complexit]' is exacerbated in open environments where independently developed autonomous agents inferoct with each ather in order ta achieve their goals. Inevitably, exceptions will occur in such MAS and these(More)
Computer forensics is a relatively young University discipline which has developed strongly in the United States and the United Kingdom but is still in its infancy in continental Europe. The national programmes and courses offered therefore differ in many ways. We report on two recently established degree programmes from two European countries: Great(More)