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Modulation of Nrf2-dependent gene transcription by bilberry anthocyanins in vivo.
In a human pilot intervention study (healthy + ileostomy probands), the questions were addressed whether in vivo consumption of an anthocyanin-rich bilberry (Vaccinium myrtillius L.) pomace extractExpand
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Modulation proliferationsassoziierter Parameter der Bioaktivität eines Heidelbeerextrakts (Vaccinium myrtillus L.) mittels Fraktionierung bzw. Mikroformulierung
Polyphenolen, insbesondere Anthocyanen, werden zahlreiche chemopraventive Wirkungen zugeschrieben. Neuere Entwicklungen in der Mikroverkapselung zielen darauf ab, solche Substanzen im Lebensmittel zuExpand
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Role of topoisomerase inhibition and DNA repair mechanisms in the genotoxicity of alternariol and altertoxin-II
Alternariol (AOH) and altertoxin-II (ALTX-II) have been demonstrated to possess genotoxic properties. However, the underlying mechanisms of action have not been fully elucidated yet. AOH has recentlyExpand
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Repair of DNA damage induced by the mycotoxin alternariol involves tyrosyl-DNA phosphodiesterase 1
Alternariol (AOH) was reported recently to act as a topoisomerase poison. To underline the relevance of topoisomerase targeting for the genotoxic properties of AOH, we addressed the question whetherExpand
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Effect of microformulation on the bioactivity of an anthocyanin-rich bilberry pomace extract ( Vaccinium myrtillus L.) in vitro.
In cell culture were compared the different release rates of anthocyanins from a bilberry pomace extract encapsulated either in food grade whey protein-based matrix capsules (WPC) or in pectinExpand
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