Christopher J. Edwards

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EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis.

Alexandra N. Colebatch, Christopher J. Edwards, +17 authors Philip G Conaghan
Annals of the rheumatic diseases
2013

OBJECTIVE To develop evidence-based recommendations on the use of imaging of the joints in the clinical management of rheumatoid arthritis (RA). METHODS The task force comprised an expert group of… (More)

Multinational evidence-based recommendations for the use of methotrexate in rheumatic disorders with a focus on rheumatoid arthritis: integrating systematic literature research and expert opinion of…

Karen Visser, Wanruchada Katchamart, +23 authors Maxime R Dougados
Annals of the rheumatic diseases
2008

OBJECTIVES To develop evidence-based recommendations for the use of methotrexate in daily clinical practice in rheumatic disorders. METHODS 751 rheumatologists from 17 countries participated in the… (More)

Mesenchymal precursor cells in the blood of normal individuals

Nathan J. Zvaifler, Lilla Marinova-Mutafchieva, +4 authors Ravinder N. Maini
Arthritis research
2000

STATEMENT OF FINDINGS: Mesenchymal precursor cells found in the blood (BMPCs) of normal persons adhere to plastic and glass and proliferate logarithmically in DMEM-20% fetal calf serum (FCS) without… (More)

Anti-TNF-induced lupus.

Emma L. Williams, Stephan D Gadola, Christopher J. Edwards
Rheumatology
2009

The use of protein-based anti-TNF-alpha therapies such as antibodies and soluble TNF-alpha receptors is commonly associated with the induction of autoantibodies, whereas anti-TNF-induced lupus (ATIL)… (More)

How accurate are diagnoses for rheumatoid arthritis and juvenile idiopathic arthritis in the general practice research database?

Sara L. Thomas, Christopher J. Edwards, Liam Smeeth, Cheryl Cooper, Andrew J Hall
Arthritis and rheumatism
2008

OBJECTIVE To identify characteristics that predict a valid rheumatoid arthritis (RA) or juvenile idiopathic arthritis (JIA) diagnosis among RA- and JIA-coded individuals in the General Practice… (More)

Naturally occurring ERAP1 haplotypes encode functionally distinct alleles with fine substrate specificity.

Emma Reeves, Christopher J. Edwards, Tim Elliott, Edward James
Journal of immunology
2013

Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims peptides for MHC class I presentation, influencing the degree and specificity of CD8(+) T cell responses. Single-nucleotide polymorphisms within… (More)

Reversible acute gastrointestinal syndrome associated with active systemic lupus erythematosus in patients admitted to hospital.

Tsui Yee Lian, Christopher J. Edwards, Siew Pang Chan, Hiok Hee Chng
Lupus
2003

Patients with systemic lupus erythematosus (SLE) frequently have gastrointestinal (GI) symptoms. These are usually self-limiting and related to treatment side-effects or concurrent illness. However,… (More)

The effect of methotrexate on cardiovascular disease in patients with rheumatoid arthritis: a systematic literature review.

Sarah L. Westlake, Alexandra N. Colebatch, +5 authors Christopher J. Edwards
Rheumatology
2010

OBJECTIVES Patients with RA have an increased prevalence of cardiovascular disease (CVD). This is due to traditional risk factors and the effects of chronic inflammation. MTX is the first-choice… (More)

Knee pain, knee osteoarthritis, and the risk of fracture.

Nigel K Arden, Sarah E. Crozier, +4 authors Cyrus Cooper
Arthritis and rheumatism
2006

OBJECTIVE Patients with osteoarthritis (OA) have increased bone mineral density; however, the association between knee OA and fracture is controversial. Few data exist on the association between knee… (More)

The BILAG-2004 index is sensitive to change for assessment of SLE disease activity

Chee-Seng Yee, Vern T. Farewell, +13 authors Caroline Gordon
Rheumatology
2009

OBJECTIVE To determine if the BILAG-2004 index is sensitive to change for assessment of SLE disease activity. METHODS This was a prospective multi-centre longitudinal study of SLE patients. At… (More)

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