Christopher J. Jackson

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We present a new low-latency system area network that provides the ultra-high bandwidth needed to fuse a collection of large SMP servers into a capability cluster. The network adapter exports a remote shared memory (RSM) model that supports low latency kernel bypass messaging. The Sun™ MPI library uses the RSM interface to implement a highly efficient(More)
BACKGROUND Dinoflagellates comprise an ecologically significant and diverse eukaryotic phylum that is sister to the phylum containing apicomplexan endoparasites. The mitochondrial genome of apicomplexans is uniquely reduced in gene content and size, encoding only three proteins and two ribosomal RNAs (rRNAs) within a highly compacted 6 kb DNA.(More)
Matrix metalloproteinase-9 (MMP9) plays an important role during angiogenesis. It is an inducible enzyme which is known to be secreted from human endothelial cells in response to phorbol myristate acetate (PMA), but thought not to be constitutively expressed. We examined the secretion of MMP9 by primary culture (P0), passage 1 (P1) and passage 2 (P2) human(More)
Cytochrome oxidase subunit 3 (Cox3) is a mitochondrion-encoded core membrane protein of complex IV of the mitochondrial respiratory chain, and consists of seven trans-membrane helices. Here we show that in diverse later-branching dinoflagellates, cox3 is consistently split into two exons in the mitochondrial genome between helices six and seven. Gene exons(More)
Multicore architectures, with their abundant on-chip resources, are effectively collections of systems-on-a-chip. The protection system for these architectures must support multiple concurrently executing operating systems (OSes) with different needs, and manage and protect the hardware's novel communication mechanisms and hardware features. Traditional(More)
Congenital myasthenic syndromes (CMSs) are rare hereditary disorders transmitted in a recessive or dominant pattern, and are caused by mutations in the genes encoding proteins of the neuromuscular junction. They are classified in three groups depending on the origin of the molecular defect. Postsynaptic defects are the most frequent and have been reported(More)
a r t i c l e i n f o In two studies (N = 504) we looked through the lens of Reinforcement Sensitivity Theory to understand the Dark Triad traits (i.e., narcissism, psychopathy, and Machiavellianism). In Study 1, the Dark Triad traits were correlated with negative affectivity, reward sensitivity, the fight system, and dysfunctional impulsivity. In Study 2,(More)
Tendon injuries cause considerable morbidity in the general adult population. The tenocytes within the tendon have the full capacity to heal the tendon intrinsically. Activated protein C (APC) plays an important role in coagulation and inflammation and more recently has been shown to promote cutaneous wound healing. In this study we examined whether APC can(More)
We present a new low-latency system area network that provides the ultra-high bandwidth needed to fuse a collection of large SMP servers into a capability cluster. The network adapter exports a remote shared memory (RSM) model that supports low latency kernel bypass messaging. The Sun™ MPI library uses the RSM interface to implement a highly efficient(More)
INTRODUCTION Rheumatoid synovial fibroblasts (RASFs) mediate joint inflammation and destruction in rheumatoid arthritis (RA). Endothelial protein C receptor (EPCR) is a specific receptor for the natural anticoagulant activated protein C (APC). It mediates the cytoprotective properties of APC and is expressed in rheumatoid synovial tissue. A recent report(More)