Christopher J. Harvey

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Fibroblastic reticular cells (FRCs) are known to inhabit T cell-rich areas of lymphoid organs, where they function to facilitate interactions between T cells and dendritic cells. However, in vivo manipulation of FRCs has been limited by a dearth of genetic tools that target this lineage. Here, using a mouse model to conditionally ablate FRCs, we(More)
Note: Affiliations are listed for identification purposes only. OVERVIEW There is widespread agreement that the Great Lakes presently are exhibiting symptoms of extreme stress from a combination of sources that include toxic contaminants, invasive species, nutrient loading, shoreline and upland land use changes, and hydrologic modifications. Many of these(More)
Inhalation of cobalt (Co) and tungsten carbide (WC) particles, but not Co or WC alone, may cause hard metal disease, risk of which does not appear to be uniform across cemented tungsten carbide (CTC) production processes. Inhalation of Co alone or in the presence of WC may cause asthma. Hypothesizing that aerosol size, chemical content, heterogeneity, and(More)
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