Christopher Hughes

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The review describes methods of de novo sequencing of peptides by mass spectrometry. De novo methods utilize computational approaches to deduce the sequence or partial sequence of peptides directly from the experimental MS/MS spectra. The concepts behind a number of de novo sequencing methods are discussed. The other approach to identify peptides by tandem(More)
—Parallel scalability allows an application to efficiently utilize an increasing number of processing elements. In this paper we explore a design space for application scalability for an inference engine in large vocabulary continuous speech recognition (LVCSR). Our implementation of the inference engine involves a parallel graph traversal through an(More)
Contemporary high-density electroencephalographic systems (hd-EEG) comprising up to 256 electrodes have inter-electrode separations of 2-4 cm. Because electric currents of the brain are believed to strongly diffuse before reaching the scalp surface, higher-density electrode coverage is often deemed unnecessary. We used an ultra-dense electroencephalography(More)
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