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Priority-dispatching rules have been studied for many decades, and they form the backbone of much industrial scheduling practice. Developing new dispatching rules for a given environment, however, is usually a tedious process involving implementing different rules in a simulation model of the facility under study and evaluating the rule through extensive(More)
The objective of this study was to make direct comparisons of the estimates of spiral and vestibular neuronal number in human archival temporal bone specimens using design-based stereology with those using the assumption-based Abercrombie method. Archival human temporal bone specimens from subjects ranging in age from 16 to 80 years old were used. The(More)
OBJECTIVE To compile a comprehensive summary of published human experience with levodopa given intravenously, with a focus on information required by regulatory agencies. BACKGROUND While safe intravenous (IV) use of levodopa has been documented for over 50 years, regulatory supervision for pharmaceuticals given by a route other than that approved by the(More)
Public transportation in rural America has existed for decades. Its providers are challenged with low populations and long distances in rural areas. Many of these rural transit providers have been in existence for many years, but ridership still remains low. These providers usually operate in a demand-response format, as opposed to large cities, where(More)
Experimental evolution of bacterial populations in the laboratory has led to identification of several themes, including parallel evolution of populations adapting to carbon starvation, heat stress, and pH stress. However, most of these experiments study growth in defined and/or constant environments. We hypothesized that while there would likely continue(More)
We recently described cytological findings in the adenohypophyses of a group of patients dying in uremia of acute renal tubular necrosis.' Dramatic changes in the acidophilic cells were interpreted as the morphological expression of altered pituitary function in response to malnutrition. Changes in the basophils were thought to result from both malnutrition(More)
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