Christopher G. Maloney

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OBJECTIVES To establish longitudinal validation of a new tool, the Asthma Symptom Tracker (AST). AST combines weekly use of the Asthma Control Test with a color-coded graph for visual trending. METHODS Prospective cohort study of children age 2 to 18 years admitted for asthma. Parents or children (n = 210) completed baseline AST assessments during(More)
The synthesis of prostanoids is regulated by cyclooxygenases (prostaglandin H synthases), which catalyze the conversion of arachidonic acid to PGH2. Cyclooxygenases are the target of aspirin and other nonsteroidal anti-inflammatory agents. In this study, we found that human polymorphonuclear leukocytes (PMNs) express the inducible isoform of cyclooxygenase,(More)
BACKGROUND Respiratory Syncytial Virus (RSV), a major cause of bronchiolitis, has a large impact on the census of pediatric hospitals during outbreak seasons. Reliable prediction of the week these outbreaks will start, based on readily available data, could help pediatric hospitals better prepare for large outbreaks. METHODS Naïve Bayes (NB) classifier(More)
Group B streptococcal (GBS) infections are associated with high morbidity and mortality. The molecular pathways mediating the pathophysiological events in GBS infection are not fully delineated. Cyclooxygenases (COX) are the enzymes that convert arachidonate to active eicosanoids. To identify the effects of GBS on eicosanoid metabolism and regulatory(More)
Information technology can improve healthcare efficiency. We developed and implemented a simple and inexpensive tool, the "Automated Case Finding and Alerting System" (ACAS), using data from an existing clinical information system to facilitate identification of potentially eligible patients for clinical trials and patient encounters for billing purposes.(More)
OBJECTIVE To evaluate admission medication reconciliation in children with medically complex conditions (MCC) by determining the availability and accuracy of five information sources and characterising admitting order errors. DESIGN Prospective quality improvement cohort study. SETTING Tertiary care free-standing children's hospital in the Intermountain(More)
Changes in auditory sensitivity as a function of signal duration were studied in two species of Old World monkeys. Testing was conducted under free-field conditions with pure tones 250, 800, 1600, and 4000 Hz in frequency. Test stimuli ranged in duration from 35-2000 ms. The results showed that the temporal integration functions for the blue monkeys were(More)
Hospital bed demands sometimes exceed capacity, leading to delays in patient admissions, transfers and cancellations of surgical procedures. Effective strategies must be in place for an efficient use of existing beds. Establishing such strategies at academic hospitals poses serious challenges. We developed and implemented a web-based software application(More)
This paper describes the development and evaluation of an innovative application designed to engage children and their parents in weekly asthma self-monitoring and self-management to prompt an early response to deteriorations in chronic asthma control, and to provide their physicians with longitudinal data to assess the effectiveness of asthma therapy and(More)
There exist many modalities for teaching and testing medical students. One method being explored is computer-based patient simulation. Traditionally, exposure to a variety of patients has been achieved through years of training under the supervision of experts in the field. Computerized patient simulation has been proposed as a method of creating a(More)