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BACKGROUND The current study was conducted to evaluate the performance of magnetic resonance (MR)-ultrasound-guided fusion biopsy in diagnosing clinically significant prostate cancer (csCaP). METHODS A total of 1042 men underwent multiparametric MR imaging (mpMRI) and fusion biopsy consecutively in a prospective trial (2009-2014). An expert reader graded(More)
PURPOSE Although kidney cancer incidence and nephrectomy rates have risen in tandem, clinical advances have generated new uncertainty regarding the optimal management of patients with small renal tumors, especially the elderly. To clarify existing practice patterns, we assessed contemporary trends in the incidence and management of patients with early-stage(More)
OBJECTIVES To characterize the contemporary use of oral-targeted therapies (ie, sunitinib, sorafenib) among patients with renal cell carcinoma (RCC) and to assess the factors associated with short-term and sequential treatment. METHODS We used an administrative claims database of privately insured patients to evaluate oral-targeted therapy use among(More)
PURPOSE We examined variation in active surveillance use in Medicare eligible men undergoing expectant treatment for early stage prostate cancer. MATERIALS AND METHODS Using SEER (Surveillance, Epidemiology and End Results) and Medicare data we identified 49,192 men diagnosed with localized prostate cancer from 2004 through 2007. Of 7,347 patients who did(More)
BACKGROUND Robot-assisted retroperitoneoscopic partial nephrectomy (RARPN) may be used for posterior renal masses or with prior abdominal surgery; however, there is relatively less familiarity with RARPN. OBJECTIVE To demonstrate RARPN technique and outcomes. DESIGN, SETTING, AND PARTICIPANTS A retrospective multicenter study of 227 consecutive RARPNs(More)
PURPOSE We performed a meta-analysis to compare treatment with α-blockers and anticholinergics (ie combination therapy) to α-blocker monotherapy to clarify the efficacy and safety of this treatment approach among men with storage urinary symptoms related to benign prostatic hyperplasia. MATERIALS AND METHODS We searched for trials of men with benign(More)
OBJECTIVES Targeted biopsy, using magnetic resonance (MR)-ultrasound (US) fusion, may allow tracking of specific cancer sites in the prostate. We aimed to evaluate the initial use of the technique to follow tumor sites in men on active surveillance of prostate cancer. METHODS AND MATERIALS A total of 53 men with prostate cancer (all T1c category)(More)
PURPOSE We describe longitudinal trends in surgeon adoption of laparoscopic radical nephrectomy. We assessed whether this technique is associated with specific surgeon and/or practice setting characteristics. METHODS AND MATERIALS We used Surveillance, Epidemiology and End Results-Medicare data to identify patients who underwent laparoscopic or open(More)
OBJECTIVE To examine trends in medical management of men with benign prostatic hyperplasia/lower urinary tract symptoms (BPH/LUTS) in relation to sentinel events specific to particular medication regimens. METHODS Using the National Ambulatory Medical Care Survey (1993-2010), we identified outpatient visits by men with BPH/LUTS. We ascertained(More)
OBJECTIVE To assess the effectiveness of a feedback and educational intervention to increase documentation of clinical tumor-node-metastasis (TNM) stage among urologists in a statewide quality improvement collaborative. METHODS The Michigan Urological Surgery Improvement Collaborative (MUSIC) is a consortium of urology practices that aims to improve the(More)