Christopher Fellows

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Current cell-based repair strategies have proven unsuccessful for treating cartilage defects and osteoarthritic lesions, consequently advances in innovative therapeutics are required and mesenchymal stem cell-based (MSC) therapies are an expanding area of investigation. MSCs are capable of differentiating into multiple cell lineages and exerting paracrine(More)
While computers have defeated the best human players in many classic board games, progress in Go remains elusive. The large branching factor in the game makes traditional adversarial search intractable while the complex interaction of stones makes it difficult to assign a reliable evaluation function. This is why most existing programs rely on hand-tuned(More)
In recent years it has become increasingly clear that articular cartilage harbours a viable pool of progenitor cells and interest has focussed on their role during development and disease. Analysis of progenitor numbers using fluorescence-activated sorting techniques has resulted in wide-ranging estimates, which may be the result of context-dependent(More)
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