Christopher Dräger

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BACKGROUND Previous work from the authors' group characterized a prolonged percutaneous blockade of the sciatic nerve in rats using bupivacaine-dexamethasone microspheres. The goals of the current study are to examine the (1) efficacy of bupivacaine microspheres with and without dexamethasone for intercostal blockade in sheep; (2) scaling of dose and(More)
The bleeding complications of gastric- and duodenal ulcers have not declined in the past 20 years. This is the leading factor for the unchanged lethality of this disease. We present our results in 31 patients with gastroduodenal ulcer bleeding. The mean age was 72, 1 years and the majority of patients had an advanced stage of ulcer disease with penetration(More)
It was the aim of the study to compare the pharmacokinetic properties of the two new estrogens, ZK 136295 and ZK 115194, with those of ethinylestradiol (EE2) after single intravenous (60 micrograms) and oral (120 and 240 micrograms) administration in 54 postmenopausal women. In particular, our objective was to examine whether one or both compounds were(More)
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