Christopher D. Chaput

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STUDY DESIGN Prospective, multicenter, randomized Food and Drug Administration approved investigational device exemption clinical trial. OBJECTIVE To evaluate the safety and effectiveness of the PCM Cervical Disc compared with anterior cervical discectomy and fusion (ACDF) in the treatment of patients with degenerative spondylosis and neurological(More)
STUDY DESIGN Retrospective radiographic review of consecutive patients with universally applied standard. OBJECTIVES To define MRI findings at the facet joints that may suggest abnormal sagittal plane translation seen on standing lateral flexion-extension (SLFE) radiographs. SUMMARY OF BACKGROUND DATA MRI findings, including facet joint orientation,(More)
STUDY DESIGN Case study with unique laboratory analysis. OBJECTIVE To present a potentially serious adverse event that may occur in unique individuals when using recombinant human bone morphogenetic protein-2 (rhBMP-2) to augment fusion in posterior cervical spine surgery. SUMMARY OF BACKGROUND DATA The use of rhBMP-2 to augment posterior cervical(More)
The methodology for the repair of critical-sized or non-union bone lesions has unpredictable efficacy due in part to our incomplete knowledge of bone repair and the biocompatibility of bone substitutes. Although human mesenchymal stem cells (hMSCs) differentiate into osteoblasts, which promote bone growth, their ability to repair bone in vivo has been(More)
BACKGROUND As the population ages, the number of proximal femoral fractures seen each year is expected to increase. Subsequent contralateral hip fractures have been reported to occur in as many as 11.8% of patients after surgical fixation of the initial fracture, but it is unknown if this rate is similar among patients managed with different surgical(More)
STUDY DESIGN Retrospective comparative study using prospectively collected data. OBJECTIVE To compare the rate of infection with and without the use of vancomycin powder application during posterior cervical instrumentation. SUMMARY OF BACKGROUND DATA Surgical site infections (SSI) are a significant source of morbidity in multilevel(More)
STUDY DESIGN Retrospective radiographic and clinical review of patients in a comprehensive trauma database. OBJECTIVE The primary aim of this study was to detect occipitocervical complex (OCC) injuries initially missed at a level 1 trauma center. SUMMARY OF BACKGROUND DATA Recent case series demonstrate that OCC injuries are potentially survivable.(More)
BACKGROUND CONTEXT Studies have suggested that the use of bone marrow aspirate (BMA) with HEALOS (DePuy Spine, Raynham, MA), a collagen-hydroxyapatite sponge (CHS), is an effective substitute for autologous iliac crest bone graft when used in fusion procedures of the lumbar spine. PURPOSE To assess clinical and radiographic outcomes after implantation of(More)
BACKGROUND Reported surgical treatment of unstable pediatric cervical spine injuries typically involves posterior fusion with internal fixation, usually with posterior wiring. PURPOSE To discuss management issues in the treatment of an unstable Salter-Harris type I pediatric cervical spine injury and surgical intervention without fusion. STUDY DESIGN A(More)
BACKGROUND Case series suggest that atlanto-occipital dissociation (AOD) is a potentially survivable injury. Intuitively, a significant neurologic injury, a high degree of initial distraction, and more severe associated injuries would decrease the likelihood of survival. However, this has never been demonstrated for this injury pattern in a statistically(More)