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STUDY DESIGN Prospective, multicenter, randomized Food and Drug Administration approved investigational device exemption clinical trial. OBJECTIVE To evaluate the safety and effectiveness of the PCM Cervical Disc compared with anterior cervical discectomy and fusion (ACDF) in the treatment of patients with degenerative spondylosis and neurological(More)
The methodology for the repair of critical-sized or non-union bone lesions has unpredictable efficacy due in part to our incomplete knowledge of bone repair and the biocompatibility of bone substitutes. Although human mesenchymal stem cells (hMSCs) differentiate into osteoblasts, which promote bone growth, their ability to repair bone in vivo has been(More)
STUDY DESIGN Retrospective radiographic review of consecutive patients with universally applied standard. OBJECTIVES To define MRI findings at the facet joints that may suggest abnormal sagittal plane translation seen on standing lateral flexion-extension (SLFE) radiographs. SUMMARY OF BACKGROUND DATA MRI findings, including facet joint orientation,(More)
BACKGROUND CONTEXT Studies have suggested that the use of bone marrow aspirate (BMA) with HEALOS (DePuy Spine, Raynham, MA), a collagen-hydroxyapatite sponge (CHS), is an effective substitute for autologous iliac crest bone graft when used in fusion procedures of the lumbar spine. PURPOSE To assess clinical and radiographic outcomes after implantation of(More)
STUDY DESIGN This study retrospectively examines outcomes of unilateral transforaminal lumbar interbody fusion (TLIF) with posterior fixation using anterior carbon fiber cages and 360 degrees fusion in spondylolisthesis. OBJECTIVES The goals were to examine the outcomes and perioperative complications of using anterior column support in the treatment of(More)
Recent studies have shown that an increase in bone ingrowth by addition of osteogenic growth factors can reduce micro motion and gross implant motion and contribute to joint implant stability through osseointegration. Platelet-rich plasma (PRP) has the potential to provide growth factors that may be conducive to osteointegration at the bone-implant(More)
OBJECT Translaminar screws (TLSs) offer an alternative to pedicle screw (PS) fixation in the upper thoracic spine. Although cadaveric studies have described the anatomy of the laminae and pedicles at T1-2, CT imaging is the modality of choice for presurgical planning. In this study, the goal was to determine the diameter, maximal screw length, and optimal(More)
OBJECT Translaminar screws (TLSs) were originally described as a safer alternative to pedicle and transarticular screw placement at C-2 in adult patients. More recently, TLSs have been used in both the cervical and thoracic spine of pediatric patients as a primary fixation technique and as a bailout procedure when dysplastic pedicle morphology prohibits(More)
STUDY DESIGN Retrospective radiographic and clinical review of patients in a comprehensive trauma database. OBJECTIVE The primary aim of this study was to detect occipitocervical complex (OCC) injuries initially missed at a level 1 trauma center. SUMMARY OF BACKGROUND DATA Recent case series demonstrate that OCC injuries are potentially survivable.(More)
BACKGROUND Case series suggest that atlanto-occipital dissociation (AOD) is a potentially survivable injury. Intuitively, a significant neurologic injury, a high degree of initial distraction, and more severe associated injuries would decrease the likelihood of survival. However, this has never been demonstrated for this injury pattern in a statistically(More)