Christopher C Liu

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The DegP protein, a multifunctional chaperone and protease, is essential for clearance of denatured or aggregated proteins from the inner-membrane and periplasmic space in Escherichia coli. To date, four natural targets for DegP have been described: colicin A lysis protein, pilin subunits and MalS from E. coli, and high-molecular-weight adherence proteins(More)
The tectorial membrane (TM) connects to the stereociliary bundles of outer hair cells (OHCs). Humans with an autosomal dominant C1509G mutation in alpha-tectorin, a protein constituent of the TM, are born with a partial hearing loss that worsens over time. The Tecta(C1509/+) transgenic mouse with the same point mutation has partial hearing loss secondary to(More)
343 The emergence of endothelial keratoplasty (EK) represents the beginning of a new era in the treatment of corneal endothelial disorders which continues to evolve. Fifteen years ago we were performing penetrating keratoplasty for Fuchs' dystrophy and bullous keratopathy but nowadays we are performing selective replacement of the diseased endothelial(More)
OBJECTIVE 1) To characterize pediatric cochlear implant performance in patients with hearing loss secondary to bacterial meningitis. 2) To evaluate performance differences in patients with and without labyrinthitis ossificans (LO). STUDY DESIGN Retrospective case review. SETTING A large university-based multidisciplinary cochlear implant program. (More)
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