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- Peter E. Light, Christopher Bladen, Robert J. Winkfein, Michael P Walsh, Robert J French
- Proceedings of the National Academy of Sciences…
- 2000
Potassium channels that are inhibited by internal ATP (K(ATP) channels) provide a critical link between metabolism and cellular excitability. Protein kinase C (PKC) acts on K(ATP) channels to… (More)
- Evgeny V. Pavlov, Christopher Bladen, Robert Winkfein, Catherine T M Diao, Perry Dhaliwal, Robert J French
- Biophysical journal
- 2005
Kinetics and voltage dependence of inactivation of a prokaryotic voltage-gated sodium channel (NaChBac) were investigated in an effort to understand its molecular mechanism. NaChBac inactivation… (More)
- Houman Khosravani, Christopher Bladen, David B. Parker, Terrance P. Snutch, John E. McRory, Gerald W. Zamponi
- Annals of neurology
- 2005
Heron and colleagues (Ann Neurol 2004;55:595-596) identified three missense mutations in the Cav3.2 T-type calcium channel gene (CACNA1H) in patients with idiopathic generalized epilepsy. None of the… (More)
- Evgeny V. Pavlov, Eleonora G. Zakharian, +4 authors Robert J French
- Biophysical journal
- 2005
We examined ion channels derived from a chloroform extract of isolated, dehydrated rat liver mitochondria. The extraction method was previously used to isolate a channel-forming complex containing… (More)
- Alaa El-Husseini, Christopher Bladen, Steven R. Vincent
- Journal of neurochemistry
- 1995
We applied reverse transcription-PCR to examine the gene expression of cyclic GMP (cGMP)-dependent protein kinase in the rat brain. A PCR product with the size predicted from the type II… (More)
- Christopher Bladen, David Loewen, Steven R. Vincent
- Journal of Chemical Neuroanatomy
- 1996
Both the atriopeptides and nitric oxide act in the nervous system by activating guanylyl cyclases to stimulate the production of cyclic GMP. Thus a key to understanding the roles of these messengers… (More)
- Alaa El-Husseini, Christopher Bladen, J A Williams, Peter Reiner, Steven R. Vincent
- Journal of neurochemistry
- 1998
Nitric oxide (NO) acts via soluble guanylyl cyclase to increase cyclic GMP (cGMP), which can regulate various targets including protein kinases. Western blotting showed that type II cGMP-dependent… (More)
- Susan M. J. Dunn, Christopher Bladen
- Biochemistry
- 1991
Detailed kinetic studies of the binding of the calcium channel antagonist (+)-[3H]PN200-110 to membrane preparations from rabbit skeletal muscle have demonstrated that, in addition to the… (More)
References 1. Dinarello CA. Biologic bases for interleukin-1 in disease. Blood 1996;87:2095–2147. 2. Griffin WS, Mrak RE. Interleukin-1 in the genesis and progression of and risk for development of… (More)
- el-Husseini A el-D, Christopher Bladen, Steven R. Vincent
- Neuroreport
- 1995
The expression of the olfactory cyclic nucleotide-gated channel (CNG1) was studied in the rat brain. Using RT-PCR, levels of CNG1 mRNA were determined relative to the expression of a constantly… (More)