Christopher Barnes

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The developmental decrease in rapid-eye-movement (REM) sleep in man occurs between birth and after puberty. We hypothesize that if this decrease in REM sleep does not occur, lifelong increases in REM sleep drive may ensue. Such disorders are characterized by hypervigilance and sensory-gating deficits, such as are present in postpubertal onset disorders like(More)
STUDY DESIGN Hyper-reflexia, measured as a decrease of low frequency-dependent depression of the H-reflex, is known to occur in both humans and animals after spinal cord injury (SCI). Previous studies have shown that passive exercise for 3 months could be used to restore low frequency-dependent depression of the H-reflex after SCI. OBJECTIVE To determine(More)
BACKGROUND Hospital length of stay (LOS) and time for a patient to reach clinical stability (TCS) have increasingly become important outcomes when investigating ways in which to combat Community Acquired Pneumonia (CAP). Difficulties arise when deciding how to handle in-hospital mortality. Ad-hoc approaches that are commonly used to handle time to event(More)
The accelerating field that can be obtained in a beam-driven plasma wakefield accelerator depends on the current of the electron beam that excites the wake. In the E-167 experiment, a peak current above 10 kA will be delivered at a particle energy of 28 GeV. The bunch has a length of a few ten micrometers and several methods are used to measure its(More)
Bayesian trial designs rely on the specification of a vague data prior to the determination of trial outcome. Phase II two-stage single arm oncology trials have a generally small sample size which may not provide the necessary amount of data to outweigh a misspecified or overly optimistic prior. To account for this issue, clinicians may wish to benchmark(More)
This paper describes approach, methodology, and potential application areas for agent technologies in C2 performance and primarily focuses on the development of agent-based constructed forces. The platform involved is the AWACS-AEDGE™. This is a distributed, real-time team decision support environment comprised of simulators, entity framework, intelligent(More)
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