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  • Mohammad T. Mazhab-Jafari, Christopher B Marshall, +6 authors Mitsuhiko Ikura
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 2015 (First Publication: 4 May 2015)
  • Significance KRAS (Kirsten rat sarcoma viral oncogene homolog) is frequently mutated in pancreatic, colon, and lung tumors, which predicts poor clinical outcome, whereas germ-line mutations areExpand
  • Adam J Middleton, Christopher B Marshall, +5 authors Peter L Davies
  • Chemistry, Medicine
  • Journal of molecular biology
  • 2012 (First Publication: 9 March 2012)
  • The grass Lolium perenne produces an ice-binding protein (LpIBP) that helps this perennial tolerate freezing by inhibiting the recrystallization of ice. Ice-binding proteins (IBPs) are also producedExpand
  • Feng Wang, Christopher B Marshall, Mitsuhiko Ikura
  • Medicine, Biology
  • Cellular and Molecular Life Sciences
  • 2012 (First Publication: 11 January 2013)
  • In eukaryotic cells, gene transcription is regulated by sequence-specific DNA-binding transcription factors that recognize promoter and enhancer elements near the transcriptional start site. SomeExpand
  • Christopher B Marshall, Tadateru Nishikawa, Masanori Osawa, Peter B Stathopulos, Mitsuhiko Ikura
  • Biology, Medicine
  • Biochemical and biophysical research…
  • 2015 (First Publication: 24 April 2015)
  • The calcium (Ca(2+)) ion is a universal signalling messenger which plays vital physiological roles in all eukaryotes. To decode highly regulated intracellular Ca(2+) signals, cells have evolved aExpand
  • Mohammad T. Mazhab-Jafari, Christopher B Marshall, +5 authors Mitsuhiko Ikura
  • Medicine, Chemistry
  • Journal of the American Chemical Society
  • 2013 (First Publication: 20 February 2013)
  • Like most Ras superfamily proteins, the GTPase domain of Ras homologue enriched in brain (Rheb) is tethered to cellular membranes through a prenylated cysteine in a flexible C-terminal region;Expand