Here, we present the draft genome sequences of 80 isolates of Burkholderia pseudomallei. The isolates represent clinical cases of melioidosis and environmental isolates from regions in Australia and Papua New Guinea where B. pseudomallei is endemic. The genomes provide further context for the diversity of the pathogen.
The ability to undertake controlled human malaria infection (CHMI) studies for preliminary evaluation of malaria vaccine candidates and anti-malaria drug efficacy has been limited by the need for access to sporozoite infected mosquitoes, aseptic, purified, cryopreserved sporozoites or blood-stage malaria parasites derived ex vivo from malaria infected… (More)
The aim of this paper is to provide nonassociative commutative loops which are semidirect products of subgroups.
A dual formulation and finite element method is proposed and analyzed for simulating the Stefan problem with surface tension. The method uses a mixed form of the heat equation in the solid and liquid (bulk) domains, and imposes a weak formulation of the interface motion law (on the solid-liquid interface) as a constraint. The basic unknowns are the heat… (More)
Elliptic fourth order variational inequalities are important problems in computational mechanics. As examples we will consider the displacement obstacle problem for simply supported Kirchhoff plates and an elliptic distributed optimal control problem with point-wise state constraints. The conforming finite element method (FEM) is expensive to use for these… (More)