Christophe Moser

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We propose and experimentally demonstrate an ultra-thin rigid endoscope (450 μm diameter) based on a passive multimode optical fiber. We use digital phase conjugation to overcome the modal scrambling of the fiber to tightly focus and scan the laser light at its distal end. By exploiting the maximum number of modes available, sub-micron resolution, high(More)
Photopolymerization is commonly used in a broad range of bioapplications, such as drug delivery, tissue engineering, and surgical implants, where liquid materials are injected and then hardened by means of illumination to create a solid polymer network. However, photopolymerization using a probe, e.g., needle guiding both the liquid and the curing(More)
Persistent holograms are recorded locally with red light in a LiNbO>(3) crystal doped with Mg and Fe. Selective erasure is realized by use of a focused UV sensitizing light. We demonstrate the recording of 50 localized images as well as selective erasure in a 4 mm x 4 mm x 4 mm crystal. A comparison of the total recording time for M holograms obtained with(More)
The application of hydrogels as load-bearing biomedical components is often limited by their mechanical properties. Often an attempt to improve a hydrogel's stiffness is accompanied by a loss of toughness and swelling properties. In this work, we show that the addition of nanofibrillated cellulose (NFC) provides a mean to tailor both the swelling and the(More)
All Rights Reserved iii To my wife, Lun iv v Acknowledgements First, I would like to express my sincere gratitude to my advisor, Professor Demetri Psaltis, for his support and guidance throughout my graduate studies at Caltech. I'll be forever indebted to him for offering me the opportunity to pursue my PhD degree at the same school as my wife, not to(More)
Photopolymerization is a common method to cure materials initially in a liquid state, such as dental implants or bone or tissue fillers. Recent advances in the development of biocompatible gel- and cement-systems open up an avenue for in situ photopolymerization. For minimally invasive surgery, such procedures require miniaturized surgical endoscopic probes(More)
Nucleus pulposus replacements have been subjected to highly controversial discussions over the last 40 years. Their use has not yet resulted in a positive outcome to treat herniated disc or degenerated disc disease. The main reason is that not a single implant or tissue replacement was able to withstand the loads within an intervertebral disc. Here, we(More)
The finite dimension of the incident beam used to read out volume holographic gratings has interesting effects on their filtering properties. As the readout beam gets narrower, there is more deviation from the ideal response predicted for monochromatic plane waves. In this paper we experimentally explore beam-width-dependent phenomena such as wavelength(More)
Multi-mode fiber (MMF) endoscopes are extremely thin and have higher spatial resolution than conventional endoscopes; however, all current MMF endoscope designs require either that the MMF remain rigid during insertion and imaging or that the orientation of the MMF be known. This limits their possible medical applications. We describe an MMF endoscope(More)