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  • Christophe Dini
  • Medicine, Biology
  • Current topics in medicinal chemistry
  • 2005 (First Publication: 1 October 2005)
  • MraY presents all necessary biological requirements to be considered as a target of interest for the discovery of novel antibacterials. Furthermore, several inhibitors aimed at this enzyme have beenExpand
  • Christophe Dini, Pascal Collette, +4 authors Jozsef Aszodi
  • Chemistry, Medicine
  • Bioorganic & medicinal chemistry letters
  • 2000 (First Publication: 1 August 2000)
  • Tunicamycins (TCMs) and liposidomycins (LPMs) are naturally occurring inhibitors of the bacterial translocase (MraY). Based on structure-activity relationship (SAR) studies, a molecular model hasExpand
  • Christophe Dini, Stanislas Didierlaurent, +6 authors Jozsef Aszodi
  • Chemistry, Medicine
  • Bioorganic & medicinal chemistry letters
  • 2002 (First Publication: 1 April 2002)
  • The synthesis and inhibitory activity against MraY of a series of simplified analogues of liposidomycins are described. These compounds were mainly obtained by performing parallel synthesis in theExpand
  • Christophe Dini, N. Drochon, S. Feteanu, Jordi Guillot, Cristina Peixoto, Jozsef Aszodi
  • Chemistry, Medicine
  • Bioorganic & medicinal chemistry letters
  • 2001 (First Publication: 1 February 2001)
  • The O-beta-D-ribofuranosyl nucleoside I is the minimal structural entity of liposidomycins maintaining enzyme inhibitory activity. Modifications performed on both the primary amine and the uracilExpand
  • Christophe Dini, N. Drochon, Jordi Guillot, Pascale Mauvais, Paul Walter, Jozsef Aszodi
  • Chemistry, Medicine
  • Bioorganic & medicinal chemistry letters
  • 2001 (First Publication: 1 February 2001)
  • O-beta-D-ribofuranosyl nucleoside I is the minimal structural entity of liposidomycins that maintains enzyme inhibitory activity on MraY. A set of compounds with hydroxyl patterns different from IExpand
  • Sandrine Demare, Bryan Slater, Gaëlle Lacombe, Delphine Breuzin, Christophe Dini
  • Chemistry, Medicine
  • Journal of chromatography. A
  • 2007 (First Publication: 1 December 2007)
  • There is a continuing need for a method which can measure logPoctanol/water accurately and precisely. Liquid-liquid partition chromatography is ideally suited for this as the retention time is aExpand