Christoph Winkler von Mohrenfels

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BACKGROUND/AIMS To evaluate the effect of corneal collagen crosslinking with riboflavin and UV-A as a treatment option for postlaser in situ keratomileusis keratectasia. METHODS Crosslinking was carried out in 22 eyes of 15 patients with iatrogenic keratectasia. Follow-up, according to a standardised protocol (uncorrected visual acuity (UCVA),(More)
PURPOSE In order to select the correct intraocular lens (IOL) for implantation, it is important to measure the eye length (biometry). The IOL Master from Zeiss-Humphry is frequently used for such measurements. Because this instrument employs an optical method, any irregularities on the corneal surface or any disturbances in corneal transparency could lead(More)
PURPOSE To evaluate the possible side effects on human and porcine cadaver eyes induced by excimer laser ablation with 3 ablation frequencies. SETTING Augenklinik, Klinikum rechts der Isar, Technische Universitaet Muenchen, Munich, Germany. METHODS Central epithelial abrasion was performed on porcine and human donor eyes. Next, the porcine eyes were(More)
PURPOSE To evaluate the vitality of epithelial cells after various exposure times to 20% ethanol and epithelial flap preparation in laser-assisted subepithelial keratectomy (LASEK) using the trypan blue dye test. SETTING University Eye Clinic Regensburg, Regensburg, Germany, and the Rayne Institute, Department of Ophthalmology, St. Thomas' Hospital,(More)
PURPOSE To develop a test based on the individual expression of collagen type IV synthesis in corneal epithelial cells to identify patients who have the potential for significant corneal haze after myopic photorefractive keratectomy (PRK). SETTING Department of Ophthalmology and the Institute of Microbiology, University of Regensburg, Germany. METHODS(More)
PURPOSE The aim of this study was to evaluate the six-month clinical results of the light adjustable lens (LAL). MATERIAL AND METHODS In 20 eyes of 12 patients with cataract a cataract surgery with implantation of a light adjustable lens has been performed. 2 ¹/₂ weeks after surgery all intraocular lens adjustments were carried out. Preoperatively,(More)
PURPOSE The aim of this study was to evaluate posterior vitreomacular adhesion as a risk factor for choroidal neovascularisation (CNV) in age-related macular degeneration (AMD). The vitreoretinal interface was examined using spectralis optical coherence tomography (Spectralis-OCT, Heidelberg Engineering). PATIENTS AND METHODS In a retrospective(More)
PURPOSE To determine the relationship between epithelial flap vitality and stromal keratocyte proliferation following two epithelial refractive techniques: epi-LASIK and laser epithelial keratomileusis (LASEK). METHODS Human corneas were maintained in organ culture and underwent standard -6.00-diopter ablation. Rates of stromal keratocyte proliferation(More)
PURPOSE Systemic anti-VEGF therapy with bevacizumab was effective in neovascular AMD in the SANA study. Intravitreal bevacizumab has the advantage that a high concentration can be achieved in the eye with a low dose. First clinical studies showed a good therapeutic effect. METHODS In a clinical study 93 patients with occult or minimal classic CNV due to(More)
PURPOSE The aim of this study is to discuss the effect and outcome of a combined photodynamic therapy and intravitreal injection of bevacizumab (1.25 mg) in occult and classic choroidal neovascularisation (CNV) due to AMD. Especially cases of occult CNV with pigment epithelium detachment (PED) are not likely to respond positively to standard photodynamic(More)