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The standard administration of the investigational Japanese encephalitis vaccine IC51 is 2 doses of 6 microg with a 28-day interval. This study investigated the immunogenicity of aExpand
  • Elisabeth Schuller, Christoph S. Klade, +4 authors Erich Tauber
  • Biology, Medicine
  • Vaccine
  • 2008 (First Publication: 1 November 2008)
  • Japanese encephalitis virus (JEV) is the leading cause of viral encephalitis in Asia with a case fatality rate up to 35% and long-term sequelae up to 75%. This active-controlled, randomized,Expand
  • Verena Schlaphoff, Christoph S. Klade, +5 authors Heiner Wedemeyer
  • Biology, Medicine
  • Vaccine
  • 2007 (First Publication: 1 September 2007)
  • Only very limited information on phenotype and function of vaccine-induced CD8+ T cells is available for humans. We investigated hepatitis C virus-specific CD8+ T cells after vaccination with the HCVExpand
  • Katrin Dubischar-Kastner, Susanne Eder, +5 authors Christoph S. Klade
  • Medicine
  • Vaccine
  • 2010 (First Publication: 19 July 2010)
  • IC51 (IXIARO, JESPECT) is a recently approved prophylactic Japanese encephalitis virus vaccine with a two-vaccine primary immunization regimen. In this phase 3 trial, after primary immunization withExpand