Christoph Kohler

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C-arm computed tomography (CT) is an innovative technique that enables a C-arm system to generate 3-D images from a set of 2-D X-ray projections. This technique can reduce treatment-related complications and may improve interventional efficacy and safety. However, state-of-the-art C-arm systems rely on a circular short scan for data acquisition, which(More)
Background—Impaired flow-dependent, endothelium-mediated vasodilation (FDD) in patients with chronic heart failure (CHF) results, at least in part, from accelerated degradation of nitric oxide by oxygen radicals. The mechanisms leading to increased vascular radical formation, however, remain unclear. Therefore, we determined endothelium-bound activities of(More)
Background—Flow-dependent, endothelium-mediated vasodilation (FDD) and activity of extracellular superoxide dismutase (EC-SOD), the major antioxidative enzyme of the arterial wall, are severely impaired in patients with coronary artery disease (CAD). We hypothesized that both ACE inhibitor (ACEI) and angiotensin II type 1 receptor antagonist (AT 1-A)(More)
Twenty four male Sprague-Dawley albino rats in three equal (n = 8) groups were injected on two consecutive days with either p-chloroamphetamine hydrochloride (PCA) (10 mg/kg), H 102/09, an inhibitor of 5-hydroxytryptamine (5-HT) uptake (20 mg/kg) half an hour before PCA, or saline (1 ml/kg). Seven days later the acquisition of a two-way active avoidance(More)
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