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EPD in its twentieth year: towards complete promoter coverage of selected model organisms
TLDR
The Eukaryotic Promoter Database (EPD) is an annotated non-redundant collection of eukarian POL II promoters, experimentally defined by a transcription start site (TSS). Expand
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The Eukaryotic Promoter Database EPD: the impact of in silico primer extension
TLDR
The Eukaryotic Promoter Database (EPD) is an annotated non-redundant collection of eukarian POL II promoters, experimentally defined by a transcription start site (TSS). Expand
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The Transcription Factor Rfx3 Regulates β-Cell Differentiation, Function, and Glucokinase Expression
OBJECTIVE Pancreatic islets of perinatal mice lacking the transcription factor Rfx3 exhibit a marked reduction in insulin-producing β-cells. The objective of this work was to unravel the cellular andExpand
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The genome of the heartworm, Dirofilaria immitis, reveals drug and vaccine targets
The heartworm Dirofilaria immitis is an important parasite of dogs. Transmitted by mosquitoes in warmer climatic zones, it is spreading across southern Europe and the Americas at an alarming pace.Expand
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Nuclear factor I revealed as family of promoter binding transcription activators
BackgroundMultiplex experimental assays coupled to computational predictions are being increasingly employed for the simultaneous analysis of many specimens at the genome scale, which quicklyExpand
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ChIP-Seq Data Reveal Nucleosome Architecture of Human Promoters
Keywords: Promoter Regions, Genetic Note: Comment on: Cell. 2007; 129(4):823-37 Reference EPFL-ARTICLE-154699doi:10.1016/j.cell.2007.11.017View record in Web of Science Record created on 2010-11-09,Expand
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RFX transcription factors are essential for hearing in mice
Sensorineural hearing loss is a common and currently irreversible disorder, because mammalian hair cells (HCs) do not regenerate and current stem cell and gene delivery protocols result only inExpand
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MER41 Repeat Sequences Contain Inducible STAT1 Binding Sites
Chromatin immunoprecipitation combined with massively parallel sequencing methods (ChIP-seq) is becoming the standard approach to study interactions of transcription factors (TF) with genomicExpand
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Analysis of subtelomeric virulence gene families in Plasmodium falciparum by comparative transcriptional profiling
The Plasmodium falciparum genome is equipped with several subtelomeric gene families that are implicated in parasite virulence and immune evasion. Members of these families are uniformly positionedExpand
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MADAP, a flexible clustering tool for the interpretation of one-dimensional genome annotation data
TLDR
We have developed a flexible one-dimensional clustering tool, called MADAP, which we make available as a web server and as standalone program. Expand
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