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PURPOSE OF REVIEW This review is on renal function in patients with spina bifida. Risk factors for renal injury as well specific issues concerning the treatment of chronic renal failure, renal replacement therapy and kidney transplantation are discussed. Relevant work published earlier than 2000 is also considered because of a lack of recent literature. (More)
BACKGROUND Low biocompatibility of peritoneal dialysis fluids (PDF) contributes to mesothelial injury. We investigated whether the heat shock proteins (HSP)-27, HSP-72, and HSP-90 are differentially induced upon exposure of mesothelial cells to PDF and whether this was affected by selective modulation of the physicochemical properties of PDF. METHODS(More)
BACKGROUND A peritoneal dialysis (PD) catheter is in place at the time of kidney transplantation in children receiving PD. Removal of the catheter eliminates the risk of catheter-related infections. However, the patient benefits from leaving the catheter in place if dialysis is necessary posttransplantation. There is currently no consensus on the proper(More)
PURPOSE OF REVIEW Obstruction can either be defined as a condition that hampers optimal renal development, or, more conservatively, as a restriction to urinary outflow that, when left untreated, will cause progressive renal deterioration. Currently, management is mostly based on the latter definition, but still remains controversial. Relevant work published(More)
Recent registry reports related short stature at the time of dialysis initiation to increased morbidity and mortality. Growth may therefore serve as an overall indicator of disease severity and therapy quality in pediatric chronic kidney disease. We studied whether early correction of uremic complications such as anemia was associated with growth failure.(More)
ZIEL: Erhebung von Patienten-charakteristika und Mortalitätsrisiko von intensivpflichtigen Frühgeborenen mit Nierenversagen mit besonderem Augenmerk auf Frühgeborene mit extrem niedrigem Geburtsgewicht. DESIGN: Retrospektive Studie mit Beschreibung des 5-Jahres-Outcome von Frühgeborenen, die im Jahre 2002 an der neonatalen Intensivstation betreut wurden,(More)
BACKGROUND The aim of our study was to ascertain the complications of chronic peritoneal home dialysis in childhood. PATIENTS 17 children were treated by ambulatory peritoneal home dialysis between 1984 and 1994 at the paediatric dialysis unit of the University Children's Hospital in Vienna, Austria. Their average age was 6.5 years (1 week to 12 years); 7(More)
Currently, there are no data available on long-term effects of angiotensin-converting enzyme inhibitors (ACE-I) on graft function in children after renal transplantation. We therefore analyzed all children who were transplanted at our institution between 1989 and 1998 and followed for at least 2 years. Those treated with ACE-I, mainly because of failure of(More)
A 14-year-old boy with tubulointerstitial nephritis and uveitis (TINU syndrome) is described. Nephropathy improved without systemic cortisone treatment, whereas uveitis relapsed and was treated with topical steroids. Blood cell immunological analysis and serum analysis revealed signs of cytotoxic T-cell, macrophage and granulocyte activation, which declined(More)