Christof Klötzsch

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BACKGROUND AND PURPOSE Dynamic autoregulation has been studied predominantly in the middle cerebral artery (MCA). Because certain clinical conditions, ie, presyncopal symptoms or hypertensive encephalopathy, suggest a higher vulnerability of autoregulation within posterior parts of the brain, we investigated whether the cerebral blood flow velocity (CBFV)(More)
OBJECTIVE Alerted by the number of patients with transient global amnesia (TGA) in whom Valsalvalike activities immediately preceded the onset of TGA, we have investigated the frequency of patent foramen ovale (PFO) as the prerequisite for paradoxical embolism. DESIGN Case series with comparison to a control group. SETTING Hospitalized and ambulatory(More)
BACKGROUND AND PURPOSE The overall mortality rate of primary pontine hemorrhage (PPH) in recent studies is 40-50%. The aim of the present study was to analyze the predictive value of clinical and neuroradiologic parameters concerning the outcome of patients with PPH. METHODS We reviewed the clinical data of 29 consecutive patients (mean age, 59 +/- 13.5(More)
BACKGROUND AND PURPOSE Carotid artery disease (CAD) is able to critically impair cerebral autoregulation which increases the risk for stroke. As therapeutic strategy largely depends on the degree of CAD, we investigated whether this gradation is also related to significant changes in autoregulatory capacity. We applied cross-spectral analysis (CSA) of(More)
The incidental ultrasonographic detection of an asymptomatic cystic pineal lesion in a young woman is described and compared with findings on magnetic resonance (MR) images. Follow-up studies obtained using both imaging modalities are presented. The results indicate that transcranial ultrasonography may represent an easy and cost-effective imaging technique(More)
Patent foramen ovale (PFO) is increasingly recognized in association with cryptogenic stroke. Using transesophageal echocardiography (TEE) and transcranial Doppler sonography with ultrasonic contrast medium (contrast-TCD), we evaluated the frequency of a PFO as the fundamental condition of paradoxical embolism in 111 patients after cerebral ischemia. There(More)
BACKGROUND Second harmonic imaging is a new ultrasound technique that allows evaluation of brain tissue perfusion after application of an ultrasound contrast agent. OBJECTIVE To evaluate the potential of this technique for the assessment of abnormal echo contrast characteristics of different brain tumours. METHODS 27 patients with brain tumours were(More)
OBJECTIVES This study applied dynamic cerebral autoregulation (DCA) testing distally to severe bilateral vertebral artery disease (BVAD). METHODS Using continuous monitoring of beat-to-beat blood pressure and transcranial Doppler of the posterior cerebral arteries (PCA) were examined in 20 patients with BVAD and 22 controls. DCA testing was based on the(More)
PURPOSE Recently developed interventional radiologic techniques, such as embolization with platinum coils, may induce thrombus formation within an aneurysm. The aim of the present study was to investigate the frequency of microemboli distal to untreated and treated cerebral aneurysms. METHODS Among a total of 110 patients treated with platinum coil(More)