Christine Smyth

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X-linked severe combined immunodeficiency (SCID-X1) results from mutations in the IL2RG gene, which encodes the common gamma chain (gammac) of the receptors for interleukin (IL)-2, 4, 7, 9, 15, and 21. Affected infants typically lack T and natural killer (NK) cells as a consequence of loss of signaling via the IL-7 receptor (IL-7R) and the IL-15R,(More)
(IL)-7 and IL-15 receptors c expression differentially affects signaling via the interleukin γ Limiting Updated information and services can be found at: (4939 articles) Immunobiology (3094 articles) Hematopoiesis and Stem Cells (564 articles) Chemokines, Cytokines, and Interleukins Articles on similar topics can be found in the following Blood collections
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