Christine Schuster

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Melatonin regulates circadian and seasonal physiology via melatonin receptors expressed in the brain. However, little is known about the signal transduction mechanisms that mediate the action of melatonin in neuronal cells. To begin to address this issue, we expressed the human MT(1) receptor in the human neuroblastoma SH-SY5Y cell line. In this cell line,(More)
Sensitization of adenylate cyclase is a recently discovered phenomenon. Melatonin can induce a sensitized response of adenylate cyclase in ovine pars tuberalis cells where the receptor for melatonin is endogenously expressed. Although the mechanism is not fully understood, sensitization of adenylate cyclase may be an important part of the mechanism by which(More)
The clinical progression of chronic myeloid leukemia (CML) from chronic phase to blast crisis is characterized by the increasing failure of myeloid precursors to differentiate into mature granulocytes. This study was undertaken to investigate the influence of Bcr-Abl and of the small molecule Abl tyrosine-kinase inhibitor imatinib mesylate on granulocyte(More)
SIS4you is an Austrian research project with the aim to empower the general public by providing information and advice how to self-protect against burglary and theft. This shall be realized by means of an Internet-based security portal, which allows a low-threshold access for the citizens and which shall be developed in co-operation with the competent(More)
The efficiency of first responder organizations in crisis and disaster situations can be greatly improved by providing timely and accurate information to the general population. However, the current technical architecture for public warning and alerting in Austria via sirens and the national broadcasting companies does not suffice for providing geo-specific(More)
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