Christine M Mermier

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OBJECTIVE To identify the physiological and anthropometric determinants of sport climbing performance. METHODS Forty four climbers (24 men, 20 women) of various skill levels (self reported rating 5.6-5.13c on the Yosemite decimal scale) and years of experience (0.10-44 years) served as subjects. They climbed two routes on separate days to assess climbing(More)
OBJECTIVES To report the physiological responses of indoor rock climbing. METHODS Fourteen experienced climbers (nine men, five women) performed three climbing trials on an indoor climbing wall. Subjects performed three trials of increasing difficulty: (a) an easy 90 degrees vertical wall, (b) a moderately difficult negatively angled wall (106 degrees),(More)
BACKGROUND The amount of limb-length discrepancy necessary to adversely affect gait parameters in older adults is unknown, with information being largely anecdotal. This investigation was conducted to determine the effects of limb-length discrepancy on gait economy and lower-extremity muscle activity in older adults. METHODS Forty-four men and women(More)
The objectives of this study are threefold: 1) to assess whether 7 days of oral glutamine (GLN) supplementation reduces exercise-induced intestinal permeability; 2) whether supplementation prevents the proinflammatory response; and 3) whether these changes are associated with upregulation of the heat shock response. On separate occasions, eight human(More)
To examine the effect ("cross-tolerance") of heat acclimation (HA) on exercise performance upon exposure to acute hypobaric hypoxia (4350 m). Eight male cyclists residing at 1600 m performed tests of maximal aerobic capacity (VO2max) at 1600 m and 4350 m, a 16 km time-trial at 4350 m, and a heat tolerance test at 1600 m before and after 10 d HA at 40°C, 20%(More)
AIMS This work explored the effects of irisin on metabolism, gene expression and mitochondrial content in cultured myocytes. METHODS C2C12 myocytes were treated with various concentrations of irisin for various durations. Glycolysis and oxidative metabolism were quantified by measurement of extracellular acidification and oxygen consumption, respectively.(More)
The purpose of this investigation was to determine the effects of transdermal estradiol (E2) replacement on substrate utilization during exercise. Amenorrheic females (N = 6) performed three exercise trials following 72 h of placebo (C 72) and 72 and 144 h of medicated transdermal estradiol (E2) treatment (E2 72 and E2 144). Exercise involved 90 min of(More)
Chronic glutamine supplementation reduces exercise-induced intestinal permeability and inhibits the NF-κB pro-inflammatory pathway in human peripheral blood mononuclear cells. These effects were correlated with activation of HSP70. The purpose of this paper is to test if an acute dose of oral glutamine prior to exercise reduces intestinal permeability along(More)
New approaches to inducing altitude acclimation in a relatively short timeframe are needed, as it is not practical for many soldiers and athletes to gain access to specialized training facilities. Acclimation to one environmental stressor could enhance adaptation to various other stressors in animals and humans. This phenomenon has been described as(More)
CONTEXT Abnormal cortisol levels are a key pathophysiological indicator of post-traumatic stress disorder (PTSD). Endogenous normalization of cortisol concentration through exercise may be associated with PTSD symptom reduction. OBJECTIVE The aim of the study was to determine whether mindfulness-based stretching and deep breathing exercise (MBX)(More)