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Fentanyl citrate is a potent opioid that can be delivered by the transdermal route in cats and dogs. Publications regarding transdermal fentanyl patches were obtained and systematically reviewed. Seven studies in cats and seven studies in dogs met the criteria for inclusion in this review. Dogs achieved effective plasma concentrations approximately 24 hours(More)
OBJECTIVE To measure the plasma fentanyl concentrations achieved over time with transdermal fentanyl patches in awake cats and cats undergoing anesthesia and ovariohysterectomy. STUDY DESIGN Randomized prospective experimental study. ANIMALS Twenty-four purpose-bred cats. METHODS Cats were randomly assigned to three groups for Part I of a larger(More)
OBJECTIVE To evaluate the effects of intravenous lidocaine (L) and ketamine (K) alone and their combination (LK) on the minimum alveolar concentration (MAC) of sevoflurane (SEVO) in dogs. STUDY DESIGN Prospective randomized, Latin-square experimental study. ANIMALS Six, healthy, adult Beagles, 2 males, 4 females, weighing 7.8 - 12.8 kg. METHODS(More)
OBJECTIVE To evaluate the effects of i.v. lidocaine (L) and ketamine (K), alone and in combination (LK), on the minimum alveolar concentration (MAC) of isoflurane (ISO) in goats. STUDY DESIGN Randomized crossover design. ANIMALS Eight, adult mixed breed castrated male goats, aged 1-2 years weighing 24-51 kg. METHODS Anesthesia was induced with ISO(More)
OBJECTIVE To evaluate selected cardiopulmonary responses to propofol 2 infusion rates in nonpretreated llamas breathing room air. ANIMALS 5 adult llamas (3 males, 2 females) with mean +/- SD body weight of 135 +/- 17.7 kg. PROCEDURE After anesthesia induction with propofol (2 mg/kg of body weight, IV), llamas received either propofol infusion 0.2(More)
OBJECTIVE To determine the minimum infusion rate (MIR) of propofol required to prevent movement in response to a noxious stimulus in dogs anesthetized with propofol alone or propofol in combination with a constant rate infusion (CRI) of ketamine. ANIMALS 6 male Beagles. PROCEDURES Dogs were anesthetized on 3 occasions, at weekly intervals, with propofol(More)
Irreversible disability in multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) is largely attributed to neuronal and axonal degeneration, which, along with inflammation, is one of the major pathological hallmarks of these diseases. Optical coherence tomography (OCT) is a non-invasive imaging tool that has been used in MS, NMOSD, and(More)
OBJECTIVE To compare plasma fentanyl concentrations attained after the application of three transdermal fentanyl patch sizes (50, 75, and 100 micrograms/hour) in dogs. DESIGN Repeated Latin square controlled study. ANIMALS Six intact, mixed-breed adult dogs (2 males, 4 females) weighing 19.9 +/- 3.4 kg. METHODS Each dog was randomly assigned to(More)
OBJECTIVE To evaluate the efficacy of the transdermal fentanyl patch in relieving perioperative pain and stress associated with ovariohysterectomy in cats. STUDY DESIGN Prospective laboratory trial. ANIMALS Twenty-four female, purpose-bred cats. METHODS Each cat was randomly assigned to groups 1-3. Group 1 received a 25-microg/h transdermal fentanyl(More)
OBJECTIVES To determine whether transdermal fentanyl patches provided cost-effective post-operative analgesia in dogs with pelvic limb injuries. STUDY DESIGN Prospective, randomized, blinded clinical trial. ANIMALS Twenty-four dogs undergoing repair of ruptured cranial cruciate ligaments or pelvic limb fractures. METHODS Dogs were randomly assigned to(More)