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Chronic traumatic encephalopathy is a progressive tauopathy that occurs as a consequence of repetitive mild traumatic brain injury. We analysed post-mortem brains obtained from a cohort of 85 subjects with histories of repetitive mild traumatic brain injury and found evidence of chronic traumatic encephalopathy in 68 subjects: all males, ranging in age from(More)
Chronic Traumatic Encephalopathy (CTE) is a neurodegenerative disease thought to be caused, at least in part, by repetitive brain trauma, including concussive and subconcussive injuries. It is thought to result in executive dysfunction, memory impairment, depression and suicidality, apathy, poor impulse control, and eventually dementia. Beyond repetitive(More)
Recent observations of the distant Universe suggest that much of the stellar mass of bright galaxies was already in place at z > 1. This presents a challenge for models of galaxy formation because massive halos are assembled late in the hierarchical clustering process intrinsic to the cold dark matter (CDM) cosmology. In this paper, we discuss a new(More)
We incorporate a model for black hole growth during galaxy mergers into the semi-analytical galaxy formation model based on ΛCDM proposed by Baugh et al.. Our black hole model has one free parameter, which we set by matching the observed zeropoint of the local correlation between black hole mass and bulge luminosity. We present predictions for the evolution(More)
OBJECTIVE The goal of this study was to examine the clinical presentation of chronic traumatic encephalopathy (CTE) in neuropathologically confirmed cases. METHODS Thirty-six adult male subjects were selected from all cases of neuropathologically confirmed CTE at the Boston University Center for the Study of Traumatic Encephalopathy brain bank. Subjects(More)
The long-term consequences of repetitive head impacts have been described since the early 20th century. Terms such as punch drunk and dementia pugilistica were first used to describe the clinical syndromes experienced by boxers. A more generic designation, chronic traumatic encephalopathy (CTE), has been employed since the mid-1900s and has been used in(More)
Youth football players may incur hundreds of repetitive head impacts (RHI) in one season. Our recent research suggests that exposure to RHI during a critical neurodevelopmental period prior to age 12 may lead to greater later-life mood, behavioral, and cognitive impairments. Here, we examine the relationship between age of first exposure (AFE) to RHI(More)
We derive constraints on cosmological parameters using the power spectrum of galaxy clustering measured from the final two-degree field galaxy redshift survey (2dF-GRS) and a compilation of measurements of the temperature power spectrum and temperature-polarization cross-correlation of the cosmic microwave background radiation. We analyse a range of(More)
We assess the detectability of baryonic acoustic oscillations (BAO) in the power spectrum of galaxies using ultra large volume N-body simulations of the hierarchical clustering of dark matter and semi-analytical modelling of galaxy formation. A step-by-step illustration is given of the various effects (nonlinear fluctuation growth, peculiar motions,(More)