Christine L. Cain

Learn More
First described together in 1988, S. lug-dunensis and S. schleiferi are coagulase-negative Staphylococcus (CNS) species that recently have emerged as potential zoonotic pathogens (Freney et al., 1988). S. lugdunensis typically has been associated with human disease, primarily skin infections and endocarditis, but recently also has been described as an(More)
BACKGROUND The prevalence of meticillin- and multidrug-resistant Staphylococcus pseudintermedius (MRSP) in canine pyoderma has been increasing in recent years; thus, treatment of these cases has become challenging. HYPOTHESIS/OBJECTIVES To compare treatment outcome (clinical resolution and treatment duration), adverse effects of medication, and concurrent(More)
OBJECTIVE To assess the degree of biological similarity (on the basis of genotype determined via pulsed-field gel electrophoresis [PFGE]) between isolates of 2 Staphylococcus schleiferi subspecies (S schleiferi subsp coagulans and S schleiferi subsp schleiferi) in clinical samples obtained from dogs. SAMPLE POPULATION 161 S schleiferi isolates from 160(More)
Staphylococcal antimicrobial resistance presents an emerging challenge for both human and veterinary medical professionals. Infections associated with methicillin- and multidrug-resistant staphylococci are increasingly encountered by veterinarians and are frequently associated with empiric therapeutic failures and limited systemic antimicrobial options.(More)
Host-microbe interactions may play a fundamental role in the pathogenesis of atopic dermatitis, a chronic relapsing inflammatory skin disorder characterized by universal colonization with Staphylococcus species. To examine the relationship between epidermal barrier function and the cutaneous microbiota in atopic dermatitis, this study used a spontaneous(More)
OBJECTIVE To define clinical differences between coagulase-positive and coagulase-negative Staphylococcus schleiferi infections in dogs and to identify risk factors for the isolation of oxacillin-resistant S schleiferi. DESIGN Retrospective case series. ANIMALS 225 dogs (yielding 225 S schleiferi isolates). PROCEDURES Information obtained from(More)
OBJECTIVE To describe clinical and histopathologic features of furunculosis in dogs following water immersion or exposure to grooming products. DESIGN Retrospective case series. ANIMALS 22 dogs with skin lesions consistent with furunculosis and a history of water immersion or grooming prior to onset. Procedures-Information collected from the medical(More)
Staphylococcus schleiferi, a Gram-positive and coagulase-variable organism, is an opportunistic human pathogen and a major cause of skin and soft tissue infections in dogs. Here, we report the first S. schleiferi genome sequence and methylome from four canine clinical isolates.
BACKGROUND Sedation is commonly used during intradermal testing (IDT). Morphine and its derivatives have long been avoided because of their histamine-releasing effects. HYPOTHESIS/OBJECTIVES Butorphanol, an opioid agonist/antagonist, will not adversely affect IDT in dogs. ANIMALS Ten client-owned dogs diagnosed with atopic dermatitis. METHODS Dogs(More)
Staphylococcus species are a leading cause of skin and soft tissue infections in humans and animals, and the antibiotics used to treat these infections are often the same. Methicillin- and multidrug-resistant staphylococcal infections are becoming more common in human and veterinary medicine. From a "One Health" perspective, this overlap in antibiotic use(More)