Christine K. Denney

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BACKGROUND Translational medicine requires the integration of knowledge using heterogeneous data from health care to the life sciences. Here, we describe a collaborative effort to produce a prototype Translational Medicine Knowledge Base (TMKB) capable of answering questions relating to clinical practice and pharmaceutical drug discovery. RESULTS We(More)
The Translational Medicine Ontology provides terminology that bridges diverse areas of translational medicine including hypothesis management, discovery research, drug development and formulation, clinical research, and clinical practice. Designed primarily from use cases, the ontology consists of essential terms that are mapped to other ontologies. It(More)
We, participants in the Translational Medicine Ontology activity of the World Wide Web Consortium's Health Care and Life Sciences Interest Group ( and members of the National Center for Biomedical Ontology (, are developing a high-level, patient-centric ontology for translational medicine which will(More)
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