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A death-domain-containing receptor that mediates apoptosis
THE cell-killing effects of the cytokines TNF-α and FasL are mediated by the distinct cell-surface receptors TNFR1, TNFR2 and Fas (also known as CD95/APO-1), which are all members of a receptorExpand
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Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K
A NUMBER of DNA viruses carry apoptosis-inhibiting genes which enable the virus to escape from the host reponse1–5. The adenovirus E1B 19K protein can inhibit apoptosis induced by El A,Expand
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Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K
Nature 374, 731-733 (1995) FIGURE 4 of this Letter should have been reproduced in colour, as shown here. The last sentence of the caption is accordingly amended to read "A blue colour indicatesExpand
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Gastric anti‐secretory, mucosal protective, anti‐pepsin and anti‐Helicobacter properties of ranitidine bismuth citrate
Ranitidine bismuth citrate is a novel compound formed from ranitidine and a bismuth citrate complex. In conscious dogs, ranitidine bismuth citrate had similar activity to ranitidine hydrochloride asExpand
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Ranitidine bismuth citrate: a novel anti‐ulcer agent with different physico‐chemical characteristics and improved biological activity to a bismuth citrate‐ranitidine admixture.
BACKGROUND: Ranitidine bismuth citrate (RBC) is a new chemical entity for the treatment of peptic ulcer disease. RESULTS: RBC is freely soluble in water (more than 600 mg/mL at pH 4.6), whereas anExpand
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The rapid purification and partial characterization of human serum angiotensinogen.
Human angiotensinogen has been purified 390-fold from serum by a rapid high-yielding procedure that involved chromatography on Blue Sepharose, phenyl-Sepharose, hydroxyapatite and immobilizedExpand
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  • Open Access
Proteolytic activities of human Campylobacter pylori and ferret gastric Campylobacter-like organism.
The levels of proteolytic activity in cell washes, lysates and pellets of C. pylori and gastric Campylobacter-like organisms isolated from humans and ferrets, respectively, have been studied usingExpand
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Substrate and inhibitor studies with human gastric aspartic proteinases.
The separation of pepsin isoenzymes 1, 2, 3 and 5 (gastricsin) in human gastric juice was effected by chromatography on Mono Q ion-exchanger, and slow-moving proteinase was purified to homogeneity byExpand
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Purification and partial characterization of rat factor D.
Rat factor D has been purified to homogeneity (10,559-fold) from serum by chromatography on CM-Sepharose Fast Flow, phenyl-Sepharose CL-4B and Mono S and has been shown to resemble its human andExpand
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Amniotic fluid calcium concentration in the prenatal diagnosis of cystic fibrosis
Calcium concentrations were measured in supernatant amniotic fluid in order to establish whether they may be used as a marker for cystic fibrosis. No difference in values were found, whether theExpand
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